Results 171 to 180 of about 30,111 (196)
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SISTER CHROMATID EXCHANGE FORMATION
Annual Review of Genetics, 1981INTRODUCTION 11 INFORMATION ABOUT CHROMOSOME ORGANIZATION PROVIDED BY SCE ANALYSIS 12 SCE INDUCTION 15 SeE Induction by Diff erent Types of DNA Damage 16 Duration of the SCE Response 22 Modulation of the seE Response 23 CORRELATES OF SCEs ........
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2007
The sister chromatid exchange (SCE) test is a relatively simple assay, sensitive to most mutagenic compounds. Its major disadvantage is that in order to detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds ...
Andrzej Wojcik, Günter Obe
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The sister chromatid exchange (SCE) test is a relatively simple assay, sensitive to most mutagenic compounds. Its major disadvantage is that in order to detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds ...
Andrzej Wojcik, Günter Obe
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Analysis of Sister‐Chromatid Exchanges
Current Protocols in Human Genetics, 1994AbstractTwo requirements for the cytogenetic analysis of sister‐chromatid exchanges (SCEs) in somatic cells are (1) a population of actively proliferating cells that will provide an adequate number of metaphases and (2) sister chromatids that in some way are differentially labeled or stained in the metaphases.
J, German, B, Alhadeff
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Sister chromatid cohesion in mitosis
Current Opinion in Genetics & Development, 1998Sister chromatid cohesion is essential for accurate chromosome segregation during the cell cycle. Newly identified structural proteins are required for sister chromatid cohesion and there may be a link in some organisms between the processes of cohesion and condensation.
S, Biggins, A W, Murray
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Sister chromatid recombination
2006Homologous recombination is a DNA repair mechanism that uses the genetic information of a homologous DNA sequence as template for repair of a DNA break. The genetic consequences of recombination depend on the choice of the molecule used as template. While sister-chromatid recombination (SCR), which uses as template for repair the identical and intact ...
Felipe Cortés-Ledesma +2 more
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Sister chromatid exchanges and heterochromatin
Human Genetics, 1981The inter- and intrachromosomal distribution patterns of SCEs obtained with or without mutagen treatment are reviewed and compared, with each other as to their relation to heterochromatin and with the distribution patterns of chromatid aberrations that occurred either "spontaneously" in chromosomes of repair-defective human syndromes or after treatment
I, Schubert, R, Rieger
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Sister chromatid exchange in newborns
Human Genetics, 1981Sister chromatid exchanges (SCE) were analyzed in the cord and postnatal blood of controlled groups of low and high birth weight infants to detect possible associations between abnormal birth weight and SCE frequency. Structural chromosome aberration rates had previously been evaluated for all infants, and possible correlations between aberration and ...
N H, Hatcher, E B, Hook
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Sister chromatid exchanges in isolabeling
Experimental Cell Research, 1974Isolabeling observed by autoradiography in sister chromatids at the second or later metaphases after incorporation of 3H-thymidine has sometimes been ascribed to an exchange between the multiple DNA duplexes in polynemic sister chromatids. An analysis reported here on the frequency and size of isolabeled regions in chromosomes of the rat kangaroo shows
D A, Gibson, D M, Prescott
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Chloramine-induced sister-chromatid exchanges
Mutation Research Letters, 1987Nitrogen-chlorine (N-Cl) derivatives are a class of long-lived oxidants produced by stimulated phagocytes which may be important mediators of the inflammatory response. Because other phagocyte-generated oxidants cause genetic damage in cultured mammalian cells, we studied the ability of the synthetic N-Cl compound, chloramine T (Cl-T), to produce ...
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Midsegmental exchanges between sister chromatids
Medical Hypotheses, 1991The model for SCE, proposed by (1), is adapted to the exchange of one or more segments located midway along the chromatid axis. In spite of conflicts in the handedness of these midsegments, the model accounts for the undistorted stacking of both sister chromatids.
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