Results 131 to 140 of about 206,590 (262)

Guidelines and good clinical practices in Italian IOM: The Bianco-Gelli Law

Brain and Spine
Giuseppe Stipa, Chiara Rabbito, Antonio Vittorino Gaddi   +2 more
doaj   +1 more source

Peripheral Neuromuscular Fatigue Responses of the Knee Extensors to Distinct Concurrent Training Protocols: A Preliminary Study. [PDF]

J Funct Morphol Kinesiol
Freitas TT, Marín-Cascales E, Marín-Pagán C, Chung LH, Martínez-Serrano A, Maffiuletti NA, Blazevich AJ, Alcaraz PE.   +7 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Reliability of Behavioral and fNIRS Neural Responses: Assessments During Posture-Inhibitory Control Dual Tasking. [PDF]

NeuroSci
Su WC, George T, Bornstein MH, Nguyen T, Gandjbakhche A.   +4 more
europepmc   +1 more source

Sitting on the floor versus sitting on a chair.

Journal of human ergology, 1973
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Polyandry: A threat or an opportunity for the sterile insect technique? [PDF]

PLoS Comput Biol
Courtois MA, van Oudenhove L, Touzeau S, Grognard F, Mailleret L.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Comparative study of the therapeutic effects of different medications on DM-associated dry eye syndrome after vitrectomy. [PDF]

Front Med (Lausanne)
Ge F, Du M, Tao Y, Sheng Y, Wang X, Du X.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source