Results 61 to 70 of about 206,590 (262)

Il ruolo dei SIT nell'evoluzione organizzativa del Comune di Catania

open access: yesGEOmedia, 2016
Il ruolo dei SIT nell'evoluzione organizzativa del Comune di ...
Redazione Redazione
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Il sistema Informativo Territoriale di Ravenne ora è in rete

open access: yesGEOmedia, 2016
Il sistema Informativo Territoriale di Ravenne è ora in ...
Giovanni Malkowski
doaj  

Pile integrity testing: Testing and results analysis [PDF]

open access: yesGrađevinski Materijali i Konstrukcije, 2019
The paper presents typical examples of pile integrity testing and the results analysis, whereby the testing methodology relies on existing ASTM standards, as well as on the testing methodology presented in the scientific paper Pile Integrity and Load ...
Ćosić Mladen   +2 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Decentramento amministrativo e sistemi territoriali (SIT/GIS)

open access: yesGEOmedia, 2016
Decentramento amministrativo e sistemi territoriali (SIT/GIS)
Calogero Ravenna
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Lombardia Informatica: una struttura al servizio della Regione

open access: yesGEOmedia, 2017
Lombardia Informatica: una struttura al servizio della ...
Redazione GEOmedia Redazione GEOmedia
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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