Results 221 to 230 of about 23,280 (257)

Mechanism of molecular interaction of sitagliptin with human DPP4 enzyme - New Insights.

Advances in Medical Sciences, 2023
PURPOSE Dipeptidyl peptidase 4 (DPP4) inactivates a range of bioactive peptides. The cleavage of insulinotropic peptides and glucagon-like peptide 1 (GLP1) by DPP4 directly influences glucose homeostasis.
M. Gonzatti, José Edvar Monteiro, A. Rocha, J. D. De Oliveira, Antônio José de Jesus Evangelista, Fátima Fonseca, V. Ceccatto, A. C. de Oliveira, José Ednésio da Cruz Freire   +8 more
semanticscholar   +1 more source

Impact of Sitagliptin in Non-Diabetic Covid-19 Patients.

Current Molecular Pharmacology, 2021
OBJECTIVE In Coronavirus disease 2019 (Covid-19), SARS-CoV-2 may use dipeptidyl peptidase 4 (DPP4) as an entry-point in different tissues expressing these receptors.
H. Al-kuraishy, A. Al-Gareeb, Naeem F. Qusty, Athanasios Alexiou, G. Batiha   +4 more
semanticscholar   +1 more source

Activation of autophagy by sitagliptin attenuates cadmium-induced testicular impairment in rats: Targeting AMPK/mTOR and Nrf2/HO-1 pathways.

Life Science, 2021
AIMS Cadmium (Cd) is a prevalent environmental contaminant that incurs deleterious health effects, including testicular impairment. Sitagliptin, a selective dipeptidyl peptidase-4 (DPP-4) inhibitor, has demonstrated marked cardio-, hepato-, and reno ...
H. Arab, Amany M Gad, Enji Reda, R. Yahia, A. Eid   +4 more
semanticscholar   +1 more source

Sitagliptin/metformin improves the fertilization rate and embryo quality in polycystic ovary syndrome patients through increasing the expression of GDF9 and BMP15: A new alternative to metformin (a randomized trial).

Journal of Reproductive Immunology, 2022
The aim of this study was to investigate the effects of sitagliptin/metformin (sitaformin), metformin and sitagliptin in PCOS patients. PCOS is a hormonal disorder and therefore the use of treatments that modulate hormone levels Like AMH, testosterone ...
Delbar Daneshjou, M. Mehranjani, S. Zadehmodarres, S. M. Shariatzadeh, Z. S. Mofarahe   +4 more
semanticscholar   +1 more source

Chitosan nanoparticles to enhance nasal absorption and brain targeting of sitagliptin to treat Alzheimer's disease

, 2020
Alzheimer's disease (AD), a highly complex, irreversible, progressive, challenging as well as fatal neurodegenerative disease of the brain, affects 35 million people around the world.
B. Wilson, Bashir Nasralla Mohamed Alobaid, K. Geetha, J. L. Jenita   +3 more
semanticscholar   +1 more source

Sitagliptin

Reactions Weekly, 2015
  +6 more sources

Sitagliptin

Reactions Weekly, 2014
  +4 more sources

Sitagliptin

Reactions Weekly, 2020
openaire   +2 more sources

Sitagliptin

Reactions Weekly, 2023
openaire   +1 more source

Sitagliptin

Reactions Weekly
  +5 more sources