Results 1 to 10 of about 372,846 (179)

Effects of dapagliflozin on podocyte damage and oxidative stress in patients with diabetic nephropathy

Diabetology & Metabolic Syndrome
Objective This study explores the effect of dapagliflozin treatment on podocyte injury and oxidative stress in patients with early diabetic nephropathy (T2DN). Methods: Clinical data from 78 patients with early T2DN, admitted to our hospital between June
Yajing Shi, Jingjing Zhang, Xiaoxiao Xin, Lixia Liu, Yaru Wu, Yanli Cheng, Li Zhang, Hong Su, Yuebin Zhao   +8 more
doaj   +1 more source

BI-LAYER TABLETS OF SITAGLIPTIN PHOSPHATE & METFORMIN HYDROCHLORIDE - PREPARATION AND EVALUATION

Prospects in Pharmaceutical Sciences
Bi-layer tablets with sitagliptin phosphate as a Immediate Release (IR) layer and metformin HCl as a Sustained Release (SR) layer were developed for hypoglycemic control. The IR formulations were formulated using Aegle marmelos gum (natural antidiabetic agent and disintegrant) by direct compression method and was found to have good pre- and post ...
Sailaja Gunnam, Sindhura T, Rajeswari Aleti, Monika Nijhawan   +3 more
openaire   +1 more source

Formulation and Evaluation of Fast Dissolving Oral Film of Sitagliptin Phosphate by Solvent Casting Method

International Journal of Ayurveda and Pharma Research
The primary objective of this study was to develop sitagliptin phosphate oral films that dissolve quickly in order to treat diabetic mellitus. The solvent casting method was employed to make the sitagliptin phosphate films that dissolve quickly. Film forming polymers HPMC E 15 and HPMC E 50 cps were utilised, along with plasticisers PEG and propylene ...
null V. Sruthi, null V. Alagarsamy, null P. Subhash Chandra Bose, null D. Saritha, null P. Srikanth Reddy   +4 more
openaire   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

A review on simultaneous method development approach for Empagliflozin and Sitagliptin phosphate

Pharmaceutical analysis plays a crucial role during the whole process of drug development, from formulating new medications to stability testing and quality control. It helps us understand the content of different dosage forms, both quantitatively and qualitatively.
openaire   +2 more sources

Preparation And Evaluation Oral Buccal Patches Of Sitagliptin Phosphate As Antidiabetic Drug

The study focuses on the development and evaluation of oral buccal patches containing Sitagliptin Phosphate, an antidiabetic drug, aimed at providing a controlled and effective delivery system for diabetes management. Sitagliptin Phosphate, a widely used DPP-4 inhibitor, was incorporated into buccal patches designed for mucosal absorption, offering a ...
openaire   +1 more source

Oligomers-model building in protonation equilibria of sitagliptin

Open Chemistry, 2013
Meloun Milan, Ferenčíková Zuzana, Niesnerová Irena, Pekárek Tomáš   +3 more
doaj   +1 more source

Development and Validation of Analytical Methods for Simultaneous Estimation of Sitagliptin Phosphate and Pioglitazone Hydrochloride [PDF]

International Journal for Pharmaceutical Research Scholars, 2018
K. G. Vaishnavi, S. T. Varsha, M. T. Nirmal, A. P. Somnath, S. K. Mallinath   +4 more
openaire   +1 more source

Maculopapular-Type Drug Eruption Caused by Sitagliptin Phosphate Hydrate: A Case Report and Mini-Review of the Published Work

Allergology International, 2014
Noriaki Nakai, Norito Katoh
doaj   +1 more source

FORMULATION AND EVALUTION OF SUSTAINED RELEASE BILAYER TABLET OF GLICAZIDE, PIOGLITAZONE HCL, AND SITAGLIPTIN PHOSPHATE

Diabetes Mellitus 2 is a progressive metabolic disease that has Insulin Resistance and impaired insulin secretion. T2DM usually produces prolonged high blood glucose levels (hyperglycaemia), which makes medication to treat T2DM require combining different types of medication over time. The research described in this paper evaluates the performance of a
openaire   +2 more sources