Results 21 to 30 of about 3,093 (146)
Drug Analytical Research, 2023 Sitagliptin phosphate (STG), used for the treatment of type 2 diabetes, is a drug that belongs to a new class called inhibitors of dipeptidyl peptidase IV (DPPIV). It is known to be the first agent of the class approved by the FDA.
Alini Dall Cortivo Lange +3 more
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Journal of Chemistry, 2013 A simple, rapid, and precise high-performance thin-layer chromatographic (HPTLC) method for simultaneous estimation of two antidiabetic drugs, metformin hydrochloride and sitagliptin phosphate, in tablet dosage form has been developed and validated ...
Darshana K. Modi +2 more
doaj +1 more source
Pakistan Journal of Pharmaceutical Sciences, 2023 Pharmaceutical substance sitagliptin has long been used to treat diabetes. However, subsequent researches have shown that sitagliptin has additional therapeutic effects. Anti-inflammatory effects are observed.
Muhammad Abdullah +6 more
doaj +1 more source
Pakistan Journal of Pharmaceutical Sciences, 2022 Reported high performance liquid chromatographic (HPLC) methods for estimating metformin hydrochloride (MET) and sitagliptin phosphate monohydrate (SIT) are either laborious or contain higher proportions of organic solvents in mobile phase, thus ...
Aqeela Raza +8 more
doaj +1 more source
Formulation And In-vitro Evaluation Of Bilayer Tablets Of Sitagliptin Phosphate
, 2021 The aim of this work was to plan mucoadhesive bilayered buccal tablets of Sitagliptin Phosphate. Sitagliptin Phosphate is the phosphate salt type of sitagliptin, an orally accessible, serious, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP4) with hypoglycemic movement.
Mayur Aware +2 more
openaire +1 more source
Is Transdermal Delivery Potential Route for Sitagliptin Phosphate: The pH Control Effect
Future Journal of Pharmaceuticals and Health Sciences, 2023 The objective of this study is to predict transdermal delivery as a potential route for sitagliptin phosphate. The partition coefficient of sitagliptin phosphate was measured in a chloroform - buffer system using the shake flask method at room temperature, and the analysis was performed under different pH conditions.
{\\"name\\":\\"Chika J Mbah\\",\\"email\\":\\"bosky24.ec@gmail.com\\",\\"affiliation\\":\\"Depart +2 more
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Effects of Dipeptidyl Peptidase-4 Inhibitors on Hyperglycemia and Blood Cyclosporine Levels in Renal Transplant Patients with Diabetes: A Pilot Study [PDF]
Endocrinology and Metabolism, 2016 BackgroundThe use of dipeptidyl peptidase-4 (DPP-4) inhibitors is increasing among renal transplant patients with diabetes. However, the glucose-lowering efficacies of various DPP-4 inhibitors and their effects on blood cyclosporine levels have not been ...
Jaehyun Bae +8 more
doaj +1 more source
Simultaneous HPLC determination of remdesivir and dexamethasone in the presence of metformin, sitagliptin, and glimepiride in a synthetic mixture and spiked human plasma [PDF]
PharmaciaThe COVID-19 pandemic has raised many questions regarding the control and therapy of type 2 diabetes and the higher risk of severe disease progression. One of the therapeutic regimens used in moderate and severe cases of COVID-19, endorsed by the World ...
Stanislav Bozhanov +2 more
doaj +3 more sources
Formulation, Development and Characterization of Transdermal Patches of Sitagliptin Phosphate
Journal of Drug Delivery and Therapeutics, 2019 Sitagliptin is a dipeptidyl peptidase 4-(DPP-4) inhibitor with glucose controlling capabilities that was effectively used for treating diabetes in the past. However, the oral administration of this drug caused such severe side effects that it was removed from the market.
Rekha Pathak +2 more
openaire +2 more sources
Results in ChemistryAn accurate analytical method is necessary for accurate quantification and stability assessment of novel antidiabetic fixed dose combination of empagliflozin and sitagliptin phosphate monohydrate.
Ashok H. Akabari +5 more
doaj +1 more source