Results 31 to 40 of about 372,846 (179)
Comparison of Serum Ketone Levels and Cardiometabolic Efficacy of Dapagliflozin versus Sitagliptin among Insulin-Treated Chinese Patients with Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2022 Background Insulin-treated patients with long duration of type 2 diabetes mellitus (T2DM) are at increased risk of ketoacidosis related to sodium-glucose co-transporter 2 inhibitor (SGLT2i).
Chi-Ho Lee +12 more
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Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells. [PDF]
PLoS ONE, 2015 Dipeptidyl peptidase IV (DPPIV/CD26) is a transmembrane glycoprotein that inactivates or degrades some bioactive peptides and chemokines. For this reason, it regulates cell proliferation, migration and adhesion, showing its role in cancer processes. This
Aline Beckenkamp +9 more
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Pharmaceutics, 2023 The purpose of this study is to derive an optimal drug release formulation with human clinical bioequivalence in developing a sitagliptin phosphate monohydrate-dapagliflozin propanediol hydrate fixed-dose combination (FDC) tablet as a treatment for type ...
So-Jin Kang, Joo-Eun Kim
doaj +1 more source
Scientific Reports, 2021 Diabetes is a complex disease characterized by hyperglycemia, dyslipidemia, and insulin resistance. Plasma advanced glycation end products (AGEs) activated the receptor for advanced glycation end products (RAGE) and the activation of RAGE is implicated ...
Chih-Pei Lin +6 more
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Acarbose Add-on Therapy in Patients with Type 2 Diabetes Mellitus with Metformin and Sitagliptin Failure: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study [PDF]
Diabetes & Metabolism Journal, 2019 BackgroundWe evaluated the efficacy and safety of acarbose add-on therapy in Korean patients with type 2 diabetes mellitus (T2DM) who are inadequately controlled with metformin and sitagliptin.MethodsA total of 165 subjects were randomized to metformin ...
Hae Kyung Yang +8 more
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Eclética Química, 2018 A simple, sensitive and reproducible spectrophotometric method was developed for the determination of sitagliptin phosphate in bulk and in pharmaceutical formulations. The proposed method is based on condensation of the primary amino group of sitagliptin
C. Bala Sekaran, A. Prameela Rani
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Drug Analytical Research, 2023 Sitagliptin phosphate (STG), used for the treatment of type 2 diabetes, is a drug that belongs to a new class called inhibitors of dipeptidyl peptidase IV (DPPIV). It is known to be the first agent of the class approved by the FDA.
Alini Dall Cortivo Lange +3 more
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Pakistan Journal of Pharmaceutical Sciences, 2023 Pharmaceutical substance sitagliptin has long been used to treat diabetes. However, subsequent researches have shown that sitagliptin has additional therapeutic effects. Anti-inflammatory effects are observed.
Muhammad Abdullah +6 more
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Pakistan Journal of Pharmaceutical Sciences, 2022 Reported high performance liquid chromatographic (HPLC) methods for estimating metformin hydrochloride (MET) and sitagliptin phosphate monohydrate (SIT) are either laborious or contain higher proportions of organic solvents in mobile phase, thus ...
Aqeela Raza +8 more
doaj +1 more source
Formulation And In-vitro Evaluation Of Bilayer Tablets Of Sitagliptin Phosphate
, 2021 The aim of this work was to plan mucoadhesive bilayered buccal tablets of Sitagliptin Phosphate. Sitagliptin Phosphate is the phosphate salt type of sitagliptin, an orally accessible, serious, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP4) with hypoglycemic movement.
Mayur Aware +2 more
openaire +1 more source