Results 51 to 60 of about 3,073 (139)

Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH, 2017
A new simple, rapid, specific, accurate, precise and novel Reverse Phase High Performance Liquid Chromatography (RP-HPLC) method has been developed for the estimation of Sitagliptin Phosphate in the pharmaceutical dosage form. The chromatographic separation for Sitagliptin was achieved with mobile phase containing methanol, Thermoscientific C18 column,
D, Sireesha, E, Sai Lakshmi, E, Sravya, Bakshi, Vasudha   +3 more
openaire   +4 more sources

Pharmacokinetics and Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Crossover Study. [PDF]

Drugs R D, 2022
Shi P, Liu X, Li T, Sun FF, Liu YP, Liu SQ, Gao XM, Ma YP, Fu Y, Cao Y.   +9 more
europepmc   +1 more source

Green and sustainable LC-APCI-MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin

BMC Chemistry
The International Agency for Research on Cancer categorized nitrosamines as potential or probable human carcinogens. Hence, nitrosamine impurities should be controlled to minimize the cancer risk.
Sriram Pepakayala, Venkata Nadh Ratnakaram, Yuvaraj Zunjarrao, Yogesh Kumar Lohia   +3 more
doaj   +1 more source

Effects of dapagliflozin on podocyte damage and oxidative stress in patients with diabetic nephropathy

Diabetology & Metabolic Syndrome
Objective This study explores the effect of dapagliflozin treatment on podocyte injury and oxidative stress in patients with early diabetic nephropathy (T2DN). Methods: Clinical data from 78 patients with early T2DN, admitted to our hospital between June
Yajing Shi, Jingjing Zhang, Xiaoxiao Xin, Lixia Liu, Yaru Wu, Yanli Cheng, Li Zhang, Hong Su, Yuebin Zhao   +8 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Formulation and Evaluation of Fast Dissolving Oral Films of Sitagliptin Phosphate by Solvent Casting Method

, 2023
Abstract The aim of this research work was to formulate fast-dissolving oral films of sitagliptin phosphate for the treatment of diabetes mellitus. The fast dissolving films of sitagliptin phosphate were prepared by solvent casting method using film forming polymers HPMC E 15 and HPMC E 50 cps and PEG and propylene glycol are used as plasticizers. All
openaire   +2 more sources

Sitagliptin phosphate [PDF]

, 2020
openaire   +3 more sources

BI-LAYER TABLETS OF SITAGLIPTIN PHOSPHATE & METFORMIN HYDROCHLORIDE - PREPARATION AND EVALUATION

Prospects in Pharmaceutical Sciences
Bi-layer tablets with sitagliptin phosphate as a Immediate Release (IR) layer and metformin HCl as a Sustained Release (SR) layer were developed for hypoglycemic control. The IR formulations were formulated using Aegle marmelos gum (natural antidiabetic agent and disintegrant) by direct compression method and was found to have good pre- and post ...
Sailaja Gunnam, Sindhura T, Rajeswari Aleti, Monika Nijhawan   +3 more
openaire   +1 more source

Formulation and Evaluation of Fast Dissolving Oral Film of Sitagliptin Phosphate by Solvent Casting Method

International Journal of Ayurveda and Pharma Research
The primary objective of this study was to develop sitagliptin phosphate oral films that dissolve quickly in order to treat diabetic mellitus. The solvent casting method was employed to make the sitagliptin phosphate films that dissolve quickly. Film forming polymers HPMC E 15 and HPMC E 50 cps were utilised, along with plasticisers PEG and propylene ...
null V. Sruthi, null V. Alagarsamy, null P. Subhash Chandra Bose, null D. Saritha, null P. Srikanth Reddy   +4 more
openaire   +1 more source

RNA-Seq Analysis of the Liver Transcriptome Reveals the Networks Regulating Treatment of Sitagliptin Phosphate plus Fuzhujiangtang Granule in the Zucker Diabetic Fatty Rats. [PDF]

Evid Based Complement Alternat Med, 2020
Guo X, Sun W, Xu G, Hou D, Zhang Z, Wu L, Liu T.   +6 more
europepmc   +1 more source