Results 61 to 70 of about 3,093 (146)

Green and sustainable LC-APCI-MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin

open access: yesBMC Chemistry
The International Agency for Research on Cancer categorized nitrosamines as potential or probable human carcinogens. Hence, nitrosamine impurities should be controlled to minimize the cancer risk.
Sriram Pepakayala   +3 more
doaj   +1 more source

Formulation and Evaluation of Fast Dissolving Oral Films of Sitagliptin Phosphate by Solvent Casting Method

open access: yes, 2023
Abstract The aim of this research work was to formulate fast-dissolving oral films of sitagliptin phosphate for the treatment of diabetes mellitus. The fast dissolving films of sitagliptin phosphate were prepared by solvent casting method using film forming polymers HPMC E 15 and HPMC E 50 cps and PEG and propylene glycol are used as plasticizers. All
openaire   +2 more sources

Effects of dapagliflozin on podocyte damage and oxidative stress in patients with diabetic nephropathy

open access: yesDiabetology & Metabolic Syndrome
Objective This study explores the effect of dapagliflozin treatment on podocyte injury and oxidative stress in patients with early diabetic nephropathy (T2DN). Methods: Clinical data from 78 patients with early T2DN, admitted to our hospital between June
Yajing Shi   +8 more
doaj   +1 more source

BI-LAYER TABLETS OF SITAGLIPTIN PHOSPHATE & METFORMIN HYDROCHLORIDE - PREPARATION AND EVALUATION

open access: yesProspects in Pharmaceutical Sciences
Bi-layer tablets with sitagliptin phosphate as a Immediate Release (IR) layer and metformin HCl as a Sustained Release (SR) layer were developed for hypoglycemic control. The IR formulations were formulated using Aegle marmelos gum (natural antidiabetic agent and disintegrant) by direct compression method and was found to have good pre- and post ...
Sailaja Gunnam   +3 more
openaire   +1 more source

Formulation and Evaluation of Fast Dissolving Oral Film of Sitagliptin Phosphate by Solvent Casting Method

open access: yesInternational Journal of Ayurveda and Pharma Research
The primary objective of this study was to develop sitagliptin phosphate oral films that dissolve quickly in order to treat diabetic mellitus. The solvent casting method was employed to make the sitagliptin phosphate films that dissolve quickly. Film forming polymers HPMC E 15 and HPMC E 50 cps were utilised, along with plasticisers PEG and propylene ...
null V. Sruthi   +4 more
openaire   +1 more source

A review on simultaneous method development approach for Empagliflozin and Sitagliptin phosphate

open access: yes
Pharmaceutical analysis plays a crucial role during the whole process of drug development, from formulating new medications to stability testing and quality control. It helps us understand the content of different dosage forms, both quantitatively and qualitatively.
openaire   +2 more sources

Preparation And Evaluation Oral Buccal Patches Of Sitagliptin Phosphate As Antidiabetic Drug

open access: yes
The study focuses on the development and evaluation of oral buccal patches containing Sitagliptin Phosphate, an antidiabetic drug, aimed at providing a controlled and effective delivery system for diabetes management. Sitagliptin Phosphate, a widely used DPP-4 inhibitor, was incorporated into buccal patches designed for mucosal absorption, offering a ...
openaire   +1 more source

Oligomers-model building in protonation equilibria of sitagliptin

open access: yesOpen Chemistry, 2013
Meloun Milan   +3 more
doaj   +1 more source

Development and Validation of Analytical Methods for Simultaneous Estimation of Sitagliptin Phosphate and Pioglitazone Hydrochloride [PDF]

open access: yesInternational Journal for Pharmaceutical Research Scholars, 2018
K. G. Vaishnavi   +4 more
openaire   +1 more source

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