Results 81 to 90 of about 372,846 (179)

Novel chemometric-driven greenness assessed spectroscopical method development and forced degradation study of sitagliptin phosphate in its bulk drug and ophthalmic formulation

Journal of Applied Pharmaceutical Research
Background: Sitagliptin phosphate (SIT), an antidiabetic drug, requires reliable analytical methods for routine quality control and stability assessment. UV-visible spectrophotometry offers a simple and economical approach; however, method robustness and
Debashis Mishra, Himansu Bhusan Samal, Diptimayee Jena, Kirtimaya Mishra   +3 more
doaj   +1 more source

Pharmacokinetics and Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Crossover Study. [PDF]

Drugs R D, 2022
Shi P, Liu X, Li T, Sun FF, Liu YP, Liu SQ, Gao XM, Ma YP, Fu Y, Cao Y.   +9 more
europepmc   +1 more source

Simultaneous Estimation of Sitagliptin and Metformin in Tablet Dosage Form by Reverse Phase High Performance Liquid Chromatography [PDF]

, 2021
In the current study, we proposed a simple, economic as well as ecologically effective technique for concurrent analysis of metformin hydrochloride and sitagliptin phosphate through reverse phase HPLC technique in combined dosage form.
Saravana Murugan, R
core  

A thermochemical approach for calcium phosphate precipitation modeling in a pellet reactor [PDF]

, 2003
A common pathway for P-recovery from wastewater is phosphate precipitation as calcium phosphates. In this paper, a thermodynamic model for phosphate precipitation is proposed based on various models of activity coefficients taking into account various ...
Cabassud, Michel, Montastruc, Ludovic, Azzaro-Pantel, Catherine, Biscans, Béatrice, Domenech, Serge   +4 more
core   +1 more source

A validated stability indicating HPLC method for determination of sitagliptin [PDF]

, 2014
comparative and stability‐indicating reversed phase high performance liquid chromatographic study have been developed and validated for sitagliptin phosphate.
Badawey, Amr Mohamed, Aboul‐Enein, Hassan Youssef, Saleh, Ola Ahmed, Badawey, Amr M., Saleh, Ola A., Aboul-Enein, Hassan Youssef, El‐Azzouny, Aida Abd El‐Sattar, El-Azzouny, Aida Abd El-Sattar   +7 more
core   +1 more source

Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin

, 2010
Bo AhrénDepartment of Clinical Sciences, Lund University, Lund, SwedenAbstract: Inhibition of dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of glucagonlike peptide-1 (GLP-1).
Ahren B, Bo Ahrén
core  

Simultaneous determination of sitagliptin and metformin in ternary mixture with sitagliptin acid degradation product [PDF]

, 2013
In this work, the acidic degradation product of sitagliptin phosphate monohydrate (STG) was synthesized, separated and its structure was elucidated.
El-Bagary, Ramzia Ismail, Ayoub, Bassam Mahfouz, Elkady, Ehab Farouk   +2 more
core   +1 more source

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin.

, 2007
AIM: To assess the efficacy and safety of a 24-week treatment with sitagliptin, a highly selective once-daily oral dipeptidyl peptidase-4 (DPP-4) inhibitor, in patients with type 2 diabetes who had inadequate glycaemic control [glycosylated haemoglobin ...
Fanurik, D, Sitagliptin Study 035 Group, Kipnes, M, Hermansen, K, Khatami, H, Stein, P, Luo, E   +6 more
core   +1 more source

Sitagliptin phosphate [PDF]

, 2020
openaire   +3 more sources

Green and sustainable LC-APCI-MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin

BMC Chemistry
The International Agency for Research on Cancer categorized nitrosamines as potential or probable human carcinogens. Hence, nitrosamine impurities should be controlled to minimize the cancer risk.
Sriram Pepakayala, Venkata Nadh Ratnakaram, Yuvaraj Zunjarrao, Yogesh Kumar Lohia   +3 more
doaj   +1 more source