Results 91 to 100 of about 372,846 (179)
Abstract The aim of this research work was to formulate fast-dissolving oral films of sitagliptin phosphate for the treatment of diabetes mellitus. The fast dissolving films of sitagliptin phosphate were prepared by solvent casting method using film forming polymers HPMC E 15 and HPMC E 50 cps and PEG and propylene glycol are used as plasticizers. All
openaire +2 more sources
Fixed-dose combination of sitagliptin and metformin for the treatment of type 2 diabetes
Jonathan K ReynoldsWashington State University, College of Pharmacy, Pullman, WA, USAAbstract: JanumetTM, a fixed dose combination of sitagliptin/metformin HCL manufactured by Merck Pharmaceuticals, has received US Food and Drug Administration approval ...
Jonathan K Reynolds
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A review of sitagliptin with special emphasis on its use in moderate to severe renal impairment [PDF]
Vinay S Eligar,1 Stephen C Bain2 1University Hospital of Wales, Cardiff, UK; 2Singleton Hospital, Swansea University, Swansea, UK Abstract: Sitagliptin is the first dipeptidylpeptidase-4 inhibitor to be used in the management of type 2 diabetes.
Bain SC, Eligar VS
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Impact of Sitagliptin on Inflammatory Biomarkers in Type 2 Diabetes Mellitus [PDF]
Background: Type 2 diabetes mellitus (T2DM) is associated with low-grade inflammatory response, which was reported to contribute to insulin resistance. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is widely used for glycemic control and has ...
Aqeel Meer AL-ZAMILY
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The phosphate balance : current developments and future outlook [PDF]
Phosphate is essential for agricultural production and therefore plays a key role in the global production of food and biofuels. There are no agricultural alternatives for phosphate, and a substantial fraction of our annual phosphate consumption is ...
Enk, R.J., van +4 more
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Highly Efficient Asymmetric Synthesis of Sitagliptin
A highly efficient synthesis of sitagliptin, a potent and selective DPP-4 inhibitor for the treatment of type 2 diabetes mellitus (T2DM), has been developed.
Yi Hsiao (771103) +15 more
core +1 more source
RNA-Seq Analysis of the Liver Transcriptome Reveals the Networks Regulating Treatment of Sitagliptin Phosphate plus Fuzhujiangtang Granule in the Zucker Diabetic Fatty Rats. [PDF]
Guo X +6 more
europepmc +1 more source
Nouf M Al-Rasheed,1 Nawal M Al-Rasheed,1,2 Iman H Hasan,1 Maha A Al-Amin,1 Hanaa N Al-Ajmi,1 Ayman M Mahmoud3 1Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 2Department of Pharmaceutical Sciences, College of ...
Al-Rasheed NM +4 more
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Nanoparticle Formulation of Sitagliptin Phosphate: A Novel Therapeutic Option for Diabetes Mellitus [PDF]
The present study was to formulate sitagliptin phosphate nanoparticles by using enteric coated polymers so that the drug is to be released in the small intestine for absorption, bypass the stomach, therefore to reduce side effects which results in ...
Gowsalya, R C
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Esther Civantos,1,2 Enrique Bosch,1 Elisa Ramirez,1 Olha Zhenyukh,1 Jesús Egido,1,2 Oscar Lorenzo,1,2 Sebastián Mas1,2 1Renal, Vascular and Diabetes Research Laboratory, IIS-Fundación Jiménez Díaz, Autonoma University ...
Ramirez E +6 more
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