Results 71 to 80 of about 372,846 (179)

Method Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form [PDF]

Method Development and Validation of RP-HPLC for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form was developed using Qualisil C18 BDS Column(150×4.5mm,5µ) as stationary phase and Potassium dihydrogen phosphate and Acetonitrile in a ratio 60:
N. Gayathri, K. Prabhakaran, A. Naveen, M. Kavinilavu, S. Maheshboopathi, M. Manikandan, M. Kaviyarasu, N. Astalakshmi, M. Surendrakumar
core   +1 more source

The potential effects of metformin and/or sitagliptin on leptin/adiponectin ratio in diabetic obese patients: a new therapeutic effect

Journal of the Pakistan Medical Association
Objective: To explore how metformin, alone or in conjunction with sitagliptin, affects the leptin/adiponectin ratio in obese type 2 diabetes mellitus patients.
Hala Aqeel Shams, Hussein Mohammed Aziz, Hayder Mutter Al-Kuraishy   +2 more
doaj   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1309-1325, May 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Formulation Development and In-Vivo, In- Vitro Evaluation of Sitagliptin Phosphate Floating Microspheres [PDF]

The purpose of the present investigation was the development and characterization of gastro-retentive floating drug delivery system for anti-diabetic drug Sitagliptin Phosphate that would retain the drug in stomach and continuously release the drug in ...
Aftab Alam, S. Rajasekaran
core   +1 more source

ENANTIOMETRIC SEPARATION OF SITAGLIPTIN IN A FIXED DOSE COMBINATION FORMULA OF SITAGLIPTIN AND METFORMIN BY A CHIRAL LIQUID CHROMATOGRAPHIC METHOD [PDF]

, 2019
Objective: Sitagliptin phosphate and metformin hydrochloride tablet is an FDA approved combination product for the treatment of diabetes mellitus type 2. There are no reported evidence for estimation of undesired (S)-sitagliptin in a combination product.
PALANISAMY, KAMARAJ, MARUTHAPILLAI, ARTHANAREESWARI, Jaishetty, Nagadeep   +2 more
core   +1 more source

Eco‐Friendly and Economical Approach for Immobilization of Thermostable ω‐Transaminase

Chemistry–Methods, Volume 6, Issue 5, May 2026.
This work presents immobilization of thermostable ω‐Transaminase on diatomaceous earth using eco‐friendly Fe3+‐tannic acid complexes. The immobilized enzyme retains optimal activity and preserves over half its activity after repeated cycles, offering a simple, economical immobilization strategy for industrial biocatalysis.
Wasia Khanam, Divya Gaur, Bijay P. Tripathi, Nidhi C. Dubey   +3 more
wiley   +1 more source

Stability indicating HPTLC method for simultaneous analysis of sitagliptin phosphate monohydrate and pioglitazone hydrochloride with greenness assessment using AGREE, ESA, BAGI and CACI

Discover Chemistry
A stability-indicating high-performance thin-layer chromatographic (HPTLC) method was developed for the simultaneous determination of sitagliptin phosphate monohydrate and pioglitazone hydrochloride in a combined antidiabetic mixture.
Riddhi B. Nagar, Rashmi Korat, Zarna Dedania, Vineet C. Jain, Ashok H. Akabari   +4 more
doaj   +1 more source

Intersecting Molecular Pathways in Cardiovascular Disease and Diabetes Mellitus: Emerging Roles of Inflammation and Therapeutics

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 4, May 2026.
Central illustration: Pathophysiological mechanisms linking diabetes mellitus and cardiovascular disease. Chronic hyperglycaemia, insulin resistance, and low‐grade inflammation contribute to endothelial dysfunction, myocardial fibrosis, and cardiomyocyte apoptosis.
Lilian Anagnostopoulou, Nikolaos Ktenopoulos, Anastasios Apostolos, Christos Fragoulis, Panayotis Vlachakis, Paschalis Karakasis, Marios Sagris, Nikias Milaras, Maria Drakopoulou, Andreas Synetos, Ioannis Kyriazis, Ioannis Ioannidis, Costas Tsioufis, Konstantinos Toutouzas   +13 more
wiley   +1 more source

Hypoglycemia associated with off-label sitagliptin use

, 2008
Heather P Whitley1,2, Kristi Kelley11Department of Pharmacy Practice, Auburn University Harrison School of Pharmacy, Auburn, AL, USA; 2Department of Community and Rural Medicine, University of Alabama School of Medicine, Tuscaloosa, AL, USAPurpose: To ...
Heather P Whitley, Kristi Kelley
core  

Analysis of published and unpublished sitagliptin (Januvia) studies in humans

, 2014
August 25, 2014 5 pm Bogotá time zone Sitagliptin (Januvia) ClinicalTrials.gov records completed before Jan 2011. Total number of records = 115Expert search terms (PubMed): http://goo.gl/pIdDaQ Records not found = 85Results = 40 Expert search terms of ...
Jorge H Ramirez (587826)
core   +1 more source