Results 91 to 100 of about 6,081,189 (307)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Effect of B-site Dopants on Magnetic and Transport Properties of LaSrCoRuO$_6$

, 2010
Effect of Co, Ru and Cu substitution at B and B' sites on the magnetic and transport properties of LaSrCoRuO$_6$ have been investigated. All the doped compositions crystallize in the monoclinic structure in the space group $P2_1/n$ indicating a double ...
A. Das, A. K. Nigam, A. Mamchik, D. Serrate, D.D. Sarma, E. Rodriguez, F. Sriti, J. Gopalakrishnan, J.-W.G. Bos, J.-W.G. Bos, J.-W.G. Boss, K. R. Priolkar, K.L. Kobayashi, M.K. Wu, N. Kamegashira, N.G. Parkinson, P. A. Bhobe, P. R. Sarode, P. S.R. Murthy, P. Tomeš, P.D. Battle, R.I. Dass, S.H. Kim, V.M. Goldschmidt, X.M. Feng, Y. Doi   +25 more
core   +1 more source

Findings for the Cleveland Achieve Model: Implementation and Early Impacts of an Employer-Based Approach to Encourage Employment Retention Among Low-Wage Workers [PDF]

, 2008
An on-site retention program at long-term nursing care facilities had little effect overall on retention of low-wage employees, aside from a small increase in retention in the short term and among subgroups with particularly high turnover ...
Cynthia Miller, Gayle Hamilton, Vanessa Martin   +2 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Asymmetric wave transmission through one dimensional lattices with cubic-quintic nonlinearity [PDF]

, 2018
One dimensional lattice with an on-site cubic-quintic nonlinear response described by a cubic-quintic discrete nonlinear Schr\"odinger equation is tested for asymmetric wave propagation. The lattice is connected to linear side chains.
Wasay, Muhammad Abdul
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Rate-equation calculations of the current flow through two-site molecular device and DNA-based junction

, 2006
Here we present the calculations of incoherent current flowing through the two-site molecular device as well as the DNA-based junction within the rate-equation approach. Few interesting phenomena are discussed in detail.
A. Aviram, A. Rakitin, A.J. Storm, A.Yu. Kasumov, B. Hartzell, B. Xu, C. Dekker, C. Kergueris, C. Wan, C. Zhou, D. Porath, D. Porath, D.H. Ha, E. Braun, G.S.M. Tong, H. Cohen, H. Watanabe, H.-W. Fink, J. Delft von, J. Lehmann, J.C. Ellenbogen, J.D. Watson, J.S. Hwang, K. Walczak, L. Cai, M. Bixon, M. Bixon, M. Zwolak, M.A. Ratner, N.C. Seeman, P. Tran, P.J. Pablo de, R. Gutiérrez, R.G. Endres, R.M. Metzger, R.M.M. Smeets, S.-J. Park, S.V. Rakhmanova, V. Bhalla, V.D. Lakhno, W. Tian, W.B. Davis, X.-Q. Li, Yu.A. Berlin, Yu.A. Berlin   +44 more
core   +1 more source

Fractional charges in pyrochlore lattices [PDF]

, 2002
A pyrochlore lattice is considered where the average electron number of electrons per site is half--integer, concentrating on the case of exactly half an electron per site.
B. KRAMER, E. MARIANI, M. SASSETTI, R. MAZZARELLO   +3 more
core   +6 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source