Results 111 to 120 of about 2,793,666 (316)

Revision of the 1844 Palestrina earthquake following the recovery of an unpublished document

open access: yesAnnals of Geophysics, 1998
The paper presented originates from the recovery of an unpublished document that reports estimated damage in the city of Palestrina (Central Italy) following the 1844 earthquake.
R. Di Giovambattista   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Sex-related differences in effect-site concentration of remifentanil for preventing anesthetic emergence cough in elderly patients

open access: yes, 2018
Sook Young Lee, Yun Yong Jeong, Byung Ho Lee, Ji Eun Kim Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Republic of Korea Purpose: Cough on anesthetic emergence should be prevented considering its dangerous ...
Jeong YY, Lee SY, Lee BH, Kim JE
core  

考虑震源不确定性的近断层高山峡谷场地地震动变异性分析

open access: yesDizhen xuebao
由于震源不确定性客观存在且对近地表地震动特性产生显著影响,尝试将乘子降维法应用至考虑震源不确定性的近断层复杂场地地震动变异性求解,将不确定性分析问题转换为有限次确定性分析,获得与蒙特卡洛模拟一致的地震动参数统计矩,其中单次确定性分析采用边界元法模拟断层破裂—传播路径—场地放大的整个物理过程。基于乘子降维法,以近走滑断层高山峡谷场地为例,分析了在近断层效应、场地效应和震源不确定性三者耦合作用下的场地地震动峰值加速度(PGA)、峰值速度(PGV)的空间分布变异性,以及关键地表点谱加速度(SA)的统计值 ...
Sibo Meng   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Effect-site concentration of remifentanil for preventing cough during emergence in elderly patients undergoing nasal surgery: a comparison with adult patients

open access: yes, 2016
Ji Young Yoo,1 Jong Yeop Kim,1 Hyun Jeong Kwak,2 Dong Chul Lee,2 Go Wun Kim,1 Sook Young Lee,1 Yun Jeong Chae1 1Department of Anaesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, 2Department of Anaesthesiology and Pain Medicine,
Kwak HJ   +6 more
core  

Effects of age on effect-site concentration of remifentanil for suppressing anesthetic emergence cough in male patients undergoing laparoscopic cholecystectomy

open access: yes, 2018
Ha Yeon Kim,1 Sook Young Lee,1 Seyoon Kang,1 Bora Kim,1 Yeo Rae Moon,2 Ji Eun Kim1 1Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Republic of Korea; 2Department of Biostatistics, Ajou University School of ...
Moon YR   +17 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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