Results 91 to 100 of about 14,635,089 (316)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Radiocarbon determinations from the Mulifanua Lapita site, Upolu, western Samoa [PDF]

, 2001
The Mulifanua ferry berth has the distinction of being the only site in Samoa with dentate-stamped Lapita wares, and is the most easterly Lapita site in the Pacific.
Petchey, Fiona, Petchey, Fiona J.
core   +1 more source

An Investigation into Near-Fault Ground Motion Characteristics and Their Influence on the Seismic Response of Typical Girder Bridges

Buildings
Near-fault ground motions significantly threaten bridges due to their distinct features, which are often inadequately considered in current seismic codes based mainly on far-field records.
Lei Zhou, Jiangli Zhang, Xu Wang, Youjia Zhang, Xinbo Jiang, Lihua Chen, Chunmei Zheng   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Publicly Funded Cleanups Site Status Report 1998: Unknown Source/Water Supply Sites, Pending Sites, No Further Action Sites, and Site Transfers

, 1998
This section describes unknown source/water supply sites, pending sites, no further action sites, and site transfers from the Publicly Funded Cleanups Site Status Report 1998.

core   +1 more source

Optimization of Structural Design in Steel Buildings Based on the Site-Specific Design Spectra of the Mexico Seismic Regulations

Geosciences
Seismic risk management in urban areas requires accurate prediction of the expected seismic hazard. The seismic design standards in the world provide the seismic design spectra (DS).
Juan Antonio Ramos-Sánchez, Sergio A. Díaz, René Sebastián Mora-Ortiz, Gabriel Polanco-Sotomayor, Francisco Magaña-Hernández   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Site Remediation Program Annual Report 1999

, 2000
The Site Remediation Program?s Annual Report 1999 focuses on regulatory and legislative action and cleanups at contaminated sites across the state.

core   +1 more source

How Might Exodus Effect Assist Users?

, 2022
Exodus Effect approach is rather than something THC supply gave to people. CBD (in any structure) animates receptor webweb destinations withinside the endocannabinoids while consumed.
Exodus Effect
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source