Results 131 to 140 of about 2,793,666 (316)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

THE EFFECTS OF SITE-SPECIFIC IRRIGATION MANAGEMENT ON SOIL MOISTURE AND POTATO PRODUCTION IN SOUTHERN ALBERTA

open access: yes, 2020
Site-specific water management can increase water use efficiency by up to 30% but determining whether adopting the technology for site-specific irrigation will be beneficial enough to consider the additional cost is still an open question. The objectives
Crawford, Danielle
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Effect of site of insemination on bovine fertility

open access: yesEurasian Journal of Veterinary Sciences, 1997
Effect ol site ol semen deposition on pregnancy rates ol artificially inseminated cattle were investigated. A total of 100 animals. 82 cows and 18 heifers, were divided into four groups and inseminated by depositing semen into corpus or cervix of the uterus or ipsi-or contralateral horn to the Graffian follicle. Pregnancy rales were 88, 72. 84 and 72 %,
Ataman, Mehmet B.   +5 more
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Comparison of sevoflurane and desflurane on effect-site concentration of remifentanil for preventing anesthetic emergence cough in elderly female patients undergoing laparoscopic cholecystectomy

open access: yes, 2018
Ha Yeon Kim,1 Yeo Rae Moon,2 Suhyun Seok,1 Bora Kim,1 Ji Eun Kim,1 Sook Young Lee1 1Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Republic of Korea; 2Office of Biostatistics, Ajou Research Institute for ...
Moon YR   +5 more
core  

Effects on Earthquake Intensity and Peak of Near-fault Velocity Pulse on Seismic Response of the Simply Supported Slab Bridge

open access: yes工程科学与技术, 2018
The main reasons for earthquake damage of bridge structures are earthquake intensity and peak of near-fault velocity pulse. Compared with other bridge types, simply supported slab bridges are more likely to be damaged in the earthquakes.
Bixiong LI   +3 more
doaj  

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