Results 131 to 140 of about 2,793,666 (316)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Site-specific water management can increase water use efficiency by up to 30% but determining whether adopting the technology for site-specific irrigation will be beneficial enough to consider the additional cost is still an open question. The objectives
Crawford, Danielle
core
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Effect of site of insemination on bovine fertility
Effect ol site ol semen deposition on pregnancy rates ol artificially inseminated cattle were investigated. A total of 100 animals. 82 cows and 18 heifers, were divided into four groups and inseminated by depositing semen into corpus or cervix of the uterus or ipsi-or contralateral horn to the Graffian follicle. Pregnancy rales were 88, 72. 84 and 72 %,
Ataman, Mehmet B. +5 more
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Ha Yeon Kim,1 Yeo Rae Moon,2 Suhyun Seok,1 Bora Kim,1 Ji Eun Kim,1 Sook Young Lee1 1Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Republic of Korea; 2Office of Biostatistics, Ajou Research Institute for ...
Moon YR +5 more
core
The main reasons for earthquake damage of bridge structures are earthquake intensity and peak of near-fault velocity pulse. Compared with other bridge types, simply supported slab bridges are more likely to be damaged in the earthquakes.
Bixiong LI +3 more
doaj

