Results 141 to 150 of about 6,118,344 (310)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Effect of site of insemination on bovine fertility
Eurasian Journal of Veterinary Sciences, 1997 Effect ol site ol semen deposition on pregnancy rates ol artificially inseminated cattle were investigated. A total of 100 animals. 82 cows and 18 heifers, were divided into four groups and inseminated by depositing semen into corpus or cervix of the uterus or ipsi-or contralateral horn to the Graffian follicle. Pregnancy rales were 88, 72. 84 and 72 %,
Ataman, Mehmet B. +5 more
openaire +3 more sources
THE EFFECT OF HAZARDOUS WASTE SITES ON PROPERTY VALUES IN ZONES OF HIGH INDUSTRIAL ACTIVITY: A HEDONIC APPROACH [PDF]
Hedonic pricing methods typically employ a distance-to-site variable to measure variation in exposure to environmental disamenities. Some environmental disamenities, like hazardous waste sites, may be spatially correlated with another prominent feature ...
Deaton, Brady J., Jr., Hoehn, John P.
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Evaluation of domestic electrical demand and its effect on low voltage network performance [PDF]
, 2012 Electrical demand in a house depends on various factors mainly being the user’s behaviour and the rating of the appliances. Some researchers have used daily domestic electrical demand profile at half hour time resolution for the energy management.
Karmacharya, Samir +3 more
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Ecología Austral, 2008 The forests of Austrocedrus chilensis in the Patagonian Andes suffer a disease known as “mal del ciprés”. The purpose of this work was to identify the relationship between A.
Ludmila La Manna +3 more
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source