Results 151 to 160 of about 2,793,666 (316)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Determining Off-Site Damages to Non-Residential Property from Leaking Underground Storage Tanks Using Contingent Valuation Analysis [PDF]

open access: yes
This research evaluates the effect of leaking underground storage tanks (LUSTs) from gas stations on nearby commercial property when the existing data is incomplete or imperfect.
Jesse Saginor, Robert A. Simons
core  

17th International Congress on Modelling and Simulation (MODSIM07) [PDF]

open access: yes, 2007
Site suitability analysis is performed to identify suitable land units (i.e. grid cells) for a specific purpose so that management decisions can be made in a site-specific manner.
Apan, A. A., Basnet, B. B.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Summary of teaching and research activities on the Hilton experimental site, East Shropshire, 1976-2010 [PDF]

open access: yes, 2010
First Version January 2000 Updated July 2000, June 2001, January 2002, October 2002, January 2003, September 2003, November 2005, March 2006, June 2006, October 2006, March 2007, July 2007, October 2007, January 2009, June 2009, March 2010The Hilton ...
Fullen, Michael A.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

PERCEIVED HAZARD AND PRODUCT CHOICE: AN APPLICATION TO RECREATIONAL SITE CHOICE

open access: yes
This study improves upon the standard "dummy variable" approach to modeling fish consumption advisories by jointly estimating a "perceived hazard" model and a site choice model.
Shaw, W. Douglass, Jakus, Paul M.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Jointed Rock Mass Effects on the Seismic Waves Scattering from the Canyon Sites in the Dam\'s Support

open access: yesعلوم آب و خاک, 2019
Seismic study of canyon sites has always been one of the important fields of seismic studies because of massive structures such as dams that are built in such sites.
M. Zabardast, F. Daneshvar Vousoughi
doaj  

Home - About - Disclaimer - Privacy