Results 81 to 90 of about 4,964,252 (354)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Acoustic telemetry system as a novel approach for evaluating the effective attraction of fish to artificial reefs

Frontiers in Marine Science, 2023
Due to there being a lack of suitable approaches for evaluating the effectiveness of artificial reefs, two experiments were designed to examine the feasibility of acoustic telemetry, a rapidly developing method for tracking aquatic animals.
Shaoliang Lyu, Hagai Nsobi Lauden, Lifei Wang, Guobao Chen, Guobao Chen, Zhichao Wang, Kun Lin, Xuefeng Wang   +7 more
doaj   +1 more source

The P-Site Loop of the Universally Conserved Bacterial Ribosomal Protein L5 Is Required for Maintaining Both Translation Rate and Fidelity [PDF]

, 2023
Mikhail Bubunenko, Alexey Korepanov
openalex   +1 more source

Site fidelity and movement patterns of reef manta rays (Mobula alfredi: Mobulidae) using passive acoustic telemetry in northern Raja Ampat, Indonesia

, 2018
Though extremely valuable to the local marine tourism industry, there is a dearth of published information on the ecology and population dynamics of reef manta rays (Mobula alfredi) in Raja Ampat, West Papua, Indonesia.
Edy Setyawan, Abraham B. Sianipar, M. Erdmann, A. Fischer, J. Haddy, Calvin S. Beale, S. Lewis, R. Mambrasar   +7 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Preliminary Studies on Site Fidelity, Residence Index, and Population Size of Irrawaddy Dolphins in West Penang, Malaysia

Oceans, 2023
The Irrawaddy dolphin is found in the coastal and estuarine areas of West Penang, Malaysia. Studies were conducted to estimate the site fidelity, residence index, and population size of Irrawaddy dolphins in West Penang. Photo-identification studies were
Nurul Filzati Ali, Leela Rajamani
doaj   +1 more source

Entanglement entropy and fidelity susceptibility in the one-dimensional spin-1 XXZ chains with alternating single-site anisotropy

, 2015
We study the fidelity susceptibility in an antiferromagnetic spin-1 XXZ chain numerically. By using the density-matrix renormalization group method, the effects of the alternating single-site anisotropy $D$ on fidelity susceptibility are investigated ...
Liu, Guang-Hua, Ren, Jie, You, Wen-Long
core   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

The Influence of Intrinsic Factors and Release Trials on Site Fidelity and Dispersal of Reintroduced Golden Parakeets (Guaruba guarouba, Aves, Psittacidae)

Diversity
Reintroducing threatened fauna has been established as a valuable conservation practice despite the obstacles that such projects still face. In avian reintroductions, elevated dispersal of released individuals is one of the main factors preventing the ...
Marcelo Rodrigues Vilarta, Maria Fernanda Naegeli Gondim, Thaís Tamamoto de Moraes, Monica Furtado, Arnaldo Algaranhar Gonçalves, Luís Fábio Silveira   +5 more
doaj   +1 more source

Quantum Monte Carlo simulations of fidelity at magnetic quantum phase transitions [PDF]

, 2009
When a system undergoes a quantum phase transition, the ground-state wave-function shows a change of nature, which can be monitored using the fidelity concept.
Alet, Fabien, Capponi, Sylvain, Schwandt, David   +2 more
core   +2 more sources