Results 181 to 190 of about 2,198,968 (261)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

An assessment of the cytochrome P450 2-hydroxyisoflavanone synthase (2-HIS) crystal structure. [PDF]

Commun Biol
Poulos TL.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Century of Progress on the Structure of APOB-100 in Atherogenic Lipoproteins. [PDF]

Circ Res
Coleman B, Woollett LA, Davidson WS.
europepmc   +1 more source

Supporting recruitment into complex trials: An embedded qualitative process evaluation in the RADICAL trial of radiofrequency denervation for chronic low back pain. [PDF]

Br J Pain
Palmer CK, Wylde V, Price C, Ashton KE, Moore AJ.   +4 more
europepmc   +1 more source

Small Molecule Activators of Protein Phosphatase 2A Exert Global Stabilizing Effects on the Scaffold PR65. [PDF]

JACS Au
Naqvi MM, Zacharopoulou M, Saha S, Banerjee A, Yilmaz SZ, Sunderlikova V, Johnson CM, Kumita JR, Yang SH, Gordon R, Ohlmeyer M, Tans SJ, Gur M, Bahar I, Itzhaki LS.   +14 more
europepmc   +1 more source

Albumin as a dynamic extracellular redox regulator: from Cys34 oxidation biomarkers to polysulfide-mediated homeostatic mechanisms and clinical applications. [PDF]

Redox Rep
Ishima Y, Watanabe H, Ikeda-Imafuku M, Maeda H, Maruyama T, Otagiri M, Chuang VTG.   +6 more
europepmc   +1 more source

Strong exciton coupling: a practical toolbox for computing interaction energies, wavefunctions, and optical spectra.

Chem Soc Rev
Ringström R, Hashemi SR, Liang Y, Hestand NJ, Börjesson K.   +4 more
europepmc   +1 more source

Metal-Dependent Effects and Crowding Robustness of Pseudomonas fluorescens Esterase I. [PDF]

Chembiochem
Ntermanakis E, Syngelaki N, Lyratzakis A, Fotiadou R, Charova S, Pavlidis IV, Giannouli A.   +6 more
europepmc   +1 more source