Results 91 to 100 of about 1,531,150 (267)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Total Oxidizable Precursor (TOP) Assay-Best Practices, Capabilities and Limitations for PFAS Site Investigation and Remediation. [PDF]
Environ Sci Technol Lett, 2023 Ateia M, Chiang D, Cashman M, Acheson C.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Internet InterventionsBackground: Family-based caregivers are increasingly important in the management of non-hospitalized lung cancer patients. However, lack of training can negatively impact care including diagnostic errors that can lead to delays in providing appropriate ...
Danielle Reynaud +3 more
doaj +1 more source
Using Immersive Virtual Reality to Enhance Social Interaction Among Older Adults: A Cross-Site Investigation. [PDF]
Innov Aging, 2023 Kalantari S +7 more
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Evaluation and Potential Uses of Site Investigation Soil Contamination Data Submitted to Uk Local Government. [PDF]
Environ Manage, 2022 Hellawell EE, Hughes SJ.
europepmc +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Multi-site Investigation of Genetic Determinants of Warfarin Dose Variability in Latinos. [PDF]
Clin Transl Sci, 2021 El Rouby N +14 more
europepmc +1 more source
, 2017 Final report and supporting documentation of the results of the Source Migration Investigation (SMI) conducted by the United States Environmental Protection Agency (EPA) on the former main plant site at the Velsicol Chemical/Pine River Site in St. Louis,
Levin, Carl, 1934-
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