Results 71 to 80 of about 3,496,435 (294)
In this project, the artist wishes to examine corporeality in the virtual realm, through the usage of the (non)-physical body of the avatar. An art installation created in the virtual world of Second Life®, which is meant to be accessed with site ...
Ayiter, Elif
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Challenges posed by demographic changes and population aging are key priorities for the Horizon 2020 Program of the European Commission. Aligned with the vision of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), the ...
João O. Malva +45 more
doaj +1 more source
Geophysical investigation of Ankashasha dam site, Southern Ethiopia [PDF]
The study area, Ankashasha dam site is found in South Nations, Nationalities and Peoples Regional state of Ethiopia. The overall objective of geophysical investigations in the study area is to assist geological studies to determine the depth of bedrock ...
Gebre Gidey Weldeabzgi +1 more
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Biological niches within human calcified aortic valves. Towards understanding of the pathological biomineralization process [PDF]
Despite recent advances, mineralization site, its microarchitecture, and composition in calcific heart valve remain poorly understood. A multiscale investigation, using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ...
Cavarretta, Elena +6 more
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Gas hydrate-bearing sediments in marine environments represent both a future energy source and a geohazard risk, prompting increasing international research attention.
Xin Feng, Lin Tan
doaj +1 more source
The membrane interface probe (MIP) is a technical device for in-situ investigation of volatile organic-contaminated sites in soil and groundwater. In recent years, it has been widely volatic organic compounds-contaminated sites.
WU Meng 1, 2, CAI Guo-jun 1,2, LIU Song-yu 1, 2, LI Xue-peng 1, 2, WANG Shui 3, ZHONG Dao-xu 3, DAI Ji-qun 4
doaj +1 more source

