Results 61 to 70 of about 23,849,714 (294)

Geological and Geotechnical Aspects of the Most Significant Deep Landslides in the Danube Area on the Territory of Vojvodina

Applied Sciences
The largest and the deepest landslides in Serbia occurred on the right valley side of the Danube. General conclusions about landslides along the Danube were obtained on the basis of their comprehensive, detailed investigations: the Sloboda bridge in Novi
Mitar Djogo, Milinko Vasić, Iva Despotović, Stefan Mihajlović   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pre-stabilization of soft soils using high-modulus columns prior to bored pile construction: an innovative approach

Open Geosciences
The construction site of a silo, which was built as two sites, consists of very soft alluvial soils. Since the superstructure loads exceeded the bearing capacity of the shallow foundation, the structure was built on a deep foundation with bored piles ...
Karaaslaner Ufuk, Arslan Çakır Eylem, Sert Sedat, Özocak Aşkın, Bol Ertan   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Geophysical investigation of Ankashasha dam site, Southern Ethiopia [PDF]

Computational Ecology and Software, 2023
The study area, Ankashasha dam site is found in South Nations, Nationalities and Peoples Regional state of Ethiopia. The overall objective of geophysical investigations in the study area is to assist geological studies to determine the depth of bedrock ...
Gebre Gidey Weldeabzgi, Mulugeta Markos Tediso   +1 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study

Frontiers in Medicine, 2018
Challenges posed by demographic changes and population aging are key priorities for the Horizon 2020 Program of the European Commission. Aligned with the vision of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), the ...
João O. Malva, João O. Malva, Alda Amado, Alda Amado, Alexandra Rodrigues, Alexandra Rodrigues, Anabela Mota-Pinto, Anabela Mota-Pinto, Anabela Mota-Pinto, Ana F. Cardoso, Ana F. Cardoso, Ana M. Teixeira, Ana M. Teixeira, Ana Todo-Bom, Ana Todo-Bom, Ana Todo-Bom, António Devesa, António Devesa, António F. Ambrósio, António F. Ambrósio, António L. Cunha, António L. Cunha, Bárbara Gomes, Bárbara Gomes, Bárbara Gomes, Carina Dantas, Carina Dantas, Cidalina Abreu, Cidalina Abreu, Isabel Santana, Isabel Santana, Isabel Santana, Jean Bousquet, João Apóstolo, João Apóstolo, Lúcia Santos, Lúcia Santos, Lúcio Meneses de Almeida, Lúcio Meneses de Almeida, Maddalena Illario, Rafaela Veríssimo, Vitor Rodrigues, Vitor Rodrigues, Manuel T. Veríssimo, Manuel T. Veríssimo, Manuel T. Veríssimo   +45 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Integrated Statistical Analysis and Spatial Modeling of Gas Hydrate-Bearing Sediments in the Shenhu Area, South China Sea

Applied Sciences
Gas hydrate-bearing sediments in marine environments represent both a future energy source and a geohazard risk, prompting increasing international research attention.
Xin Feng, Lin Tan
doaj   +1 more source