Results 51 to 60 of about 1,531,150 (267)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Subsurface Profile Mapping using 3-D Compressive Wave Imaging
MATEC Web of Conferences, 2017 Geotechnical site investigation related to subsurface profile mapping was commonly performed to provide valuable data for design and construction stage based on conventional drilling techniques.
Hazreek Z A M +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cyclic resistance evaluation of marine clay based on CPTu data: a case study of Shaba Wind Farm
Frontiers in Marine ScienceThe offshore wind farm industry has recently experienced significant global growth. This study presents a thorough site investigation and analysis of the cyclic resistance of marine clay for offshore foundation design, using the Shaba wind farm in ...
Qi Wu +4 more
doaj +1 more source
Bayesian sampling design for contaminated land investigation [PDF]
, 2009 The problem of sampling design for contaminated land investigation is approached using Bayesian methods. We develop a decision tool designed to aid site investigators and decision makers in the process of site investigation.
O’Neil, Rebecca, O'Neil, Rebecca
core
Site Investigation Guide for Mechanistic-Empirical Design of California Pavements [PDF]
, 2022 This document provides guidance on conducting site investigations for new highway construction and widening, rehabilitation, and reconstruction of existing roads. Site investigation is an important part of the pavement design process. This guide has been
Harvey, John, Wu, Rongzong, Jones, David
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
GeotechnicsThis paper assesses the effectiveness of different unsupervised Bayesian changepoint detection (BCPD) methods for identifying soil layers, using data from cone penetration tests (CPT). It compares four types of BCPD methods: a previously utilised offline
Stephen K. Suryasentana +2 more
doaj +1 more source