Results 211 to 220 of about 3,496,435 (294)

Pathophysiology and histological anomalies in testicular tissues of Calosoma olivieri exposed to heavy metals generated by pesticide industries. [PDF]

Sci Rep
El-Samad LM, Arafat EA, Hussein HK, Kheirallah N, Radwan EH, Meshaal H, Hassan MA.   +6 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Survey of Antimicrobial-Resistant Bacteria Isolated from Rivers in Japan, Indonesia and Nepal. [PDF]

Pathogens
Osawa K, Nomoto R, Suzuki T, Maeda T, Rai G, Kinoshita S, Nakanishi N, Raharjo D, Kameoka M, Fujisawa M, Rai SK, Kuntaman K, Shirakawa T.   +12 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

FORWARD: Dataset of a forwarder operating in rough terrain. [PDF]

Data Brief
Lundbäck M, Wallin E, Häggström C, Nyström M, Grönlund A, Richardson M, Jönsson P, Arnvik W, Hedström L, Fälldin A, Servin M.   +10 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Phytoplankton Diversity in the Northern Adriatic Sea: Insights and Inconsistencies from Microscopy and Metabarcoding. [PDF]

Biology (Basel)
Montali G, Neri F, Banchi E, Cerino F, Turk Dermastia T, Francé J, Mozetič P, Pelusi A, Romagnoli T, Ubaldi M, Totti C, Accoroni S.   +11 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Effects of a native avian predator (weka; Gallirallus australis) and colony density on breeding success of a burrow-nesting seabird (tītī; Ardenna grisea). [PDF]

PLoS One
Carpenter JK, Fletcher D, Arbuckle J, Coleman M, Goodsell B, Gormley A, Metzger A, Moss T, Orwin KH, Rakiura Tītī Islands Administering Body, Rakiura Tītī Committee, Scott D, Sutton L, Thompson TDW, Timoti P, Whitehead A, Lyver PO.   +16 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source