Results 61 to 70 of about 4,417,514 (289)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A new model to support the personalised management of a quality e-commerce service

, 2003
The paper presents an aiding model to support the management of a high quality e-commerce service. The approach focuses on the service quality aspects related to customer relationship management (CRM). Knowing the individual characteristics of a customer,
Franceschini, Fiorenzo, Gianni', G.
core   +1 more source

Incidence of wrong-site surgery list errors for a 2-year period in a single national health service board [PDF]

, 2017
Introduction: Wrong-site/side surgical "never events" continue to cause considerable harm to patients, healthcare professionals, and organizations within the United Kingdom.
Bowie, Paul, Ferguson, Lorna, Geraghty, Alistair, McIlhenny, Craig   +3 more
core   +1 more source

Carbapenem Resistance in Three Hospitals in India: A Need for Strengthening Infection Prevention and Control Practices

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Carbapenem-resistant (CR) organisms (CROs) pose a serious public health threat. We examined the burden of CRO colonization, the proportion of CROs among clinical isolates, and infection prevention and control (IPC) practices in three ...
Bharat Randive, Akash Patel, Rajesh Karyakarte, Shaoli Basu, Shahzad Mirza, Sweety Singh, Mrunmayi Naik, Kavita Sangma, Sarah Fisseha, Anushruti Gupta, Sarah Sabour, Meghan Murray, Amelia S. Bhatnagar, Matthew L Robinson, Melanie Curless, Patricia J Simner   +15 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Good Laboratory Practice in Analytical Chemistry with Modern Laboratory Management

Proceedings, 2020
Analytical chemistry is experiencing dramatic, turbulent change beyond laboratory and laboratory management control. Technological innovations, staffing demographics, new business models, automation, industry consolidation, society, regulatory ...
Jacobus (Koos) Frederick van Staden
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Characterizing water quality and hydrologic properties of urban streams in central Virginia [PDF]

, 2019
The objective of this study was to characterize water quality and hydrologic properties of urban streams in the Richmond metropolitan area. Water quality data were analyzed for six urban sites and two non-urban sites.
Lucas, Rikki
core   +1 more source

Developing quality e-learning sites

ASCILITE Publications, 2009
The e-learning interface design should be a core, integrated component of the overall design of on-line units. The interface design should be determined by how people learn and the tasks they need to perform. This should be driven by a pedagogical, not technological, approach which identifies learning outcomes (Guralnick, 2008).
openaire   +1 more source