Results 201 to 210 of about 2,089,094 (303)

Heme oxygenase 1 activity mediates red blood cell clearance and tail fin regeneration in zebrafish larvae. [PDF]

Sci Rep
Mirza A, Crawte S, Muñoz-Montecinos C, Mukherjee S, Lieschke GJ, Allende ML, Morales Castro RA.   +6 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Native Mass Spectrometry Reveals Binding Modes of the Tumor Suppressor Protein p53 to Different DNA Response Elements. [PDF]

J Am Soc Mass Spectrom
Siefke E, Arlt C, Sinz A.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

An observational study to test the potency of GLP-grade phenol-free lyophilised leishmanin antigen formulation. [PDF]

EBioMedicine
Pacheco-Fernandez T, Klenow L, Inoue SI, Singh KP, Valanezhad F, Markle H, Azodi N, Brino M, Bakytbek S, Hobson C, Jain I, Talgaonkar P, Shukla S, Kardile P, Kaviraj S, Silva LO, Borba PB, Santana M, Costa T, Matlashewski G, Carvalho LP, Carvalho EM, de Oliveira CI, Satoskar AR, Singh S, Hamano S, Gannavaram S, Nakhasi HL.   +27 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Unloading Reloading Rule for a One-dimensional Non-linear Model for Site Response Analysis

, 2015
Yniesta, Samuel, Brandenberg, Scott J.
core  

Recent developments in site response analysis and microzonation

Procedia Structural Integrity
Atilla Ansal, Shima Shamekhi
openaire   +1 more source

Evaluation of a Pilot Digital Antibiotic Tool. [PDF]

Clin Teach
Bowen J, Mollman J, Herchline D, Alex B, Pickering S, Girdwood ST.   +5 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source