Results 211 to 220 of about 30,097,494 (296)

Unloading Reloading Rule for a One-dimensional Non-linear Model for Site Response Analysis

, 2015
Yniesta, Samuel, Brandenberg, Scott J.
core   +1 more source

GPER and EGFR cross-talk highlight aldosterone- and MR antagonist-induced NO production in cultured endothelial cells. [PDF]

Front Pharmacol
Paredes R, Donoso MV, Lagos CF, Cárdenas C, Acuña-Castillo C, Valdes D, Constandil L, Huidobro-Toro JP.   +7 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Optimizing Cancer Vaccinations Using a Physiologically-Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model. [PDF]

Adv Sci (Weinh)
R Nikmaneshi M, P Padera T, L Munn L.
europepmc   +1 more source

Response to health physics: response to Chen

, 2009
Chang WP; 王榮德Response to health physics: response to Chen, Chang WP;Wang Jung-DerResponse to health physics: response to Chen   +1 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The Next Frontier in Quantitative Co-Clinical Imaging to Advance Functional Precision Oncology. [PDF]

Clin Cancer Res
Shoghi KI, Badea CT, Peehl DM, Chenevert TL, Daldrup-Link HE, Hawkins DS, Houghton AM, Kinahan PE, Lewis MT, Ma CX, Manning HC, Miyaoka RS, Mowery YM, O'Connor JP, O'Dwyer PJ, Ross BD, Sriram R, Yankeelov TE, Zhou R, Kurhanewicz J, Mankoff DA.   +20 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Response to "Methodological Considerations on Coding Analysis and Sampling in a Study of ED Patient Expectations". [PDF]

Acad Emerg Med
Chien LJ, Lawless A, Dahm MR.
europepmc   +1 more source