Results 91 to 100 of about 2,905,224 (291)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Performance based concrete quality assessment with gas permeability testing on site

open access: yesFrontiers in Built Environment
In terms of sustainability and durability, performance-based design is becoming increasingly important for the quality assessment of concrete structures.
Lisa Ptacek   +12 more
doaj   +1 more source

FSA field test [PDF]

open access: yes
The 12 continental remote sites were decommissioned. Testing was consolidated into a five-site network consisting of the four Southern California sites and a new Florida site. 16 kW of new state-of-the-art modules were deployed at the five sites. Testing
Jaffe, P., Lee, R. E., Weaver, R. W.
core   +1 more source

First results of site testing program at Mt. Shatdzhatmaz in 2007 - 2009

open access: yes, 2010
We present the first results of the site testing performed at Mt.~Shatdzhatmaz at Northern Caucasus, where the new Sternberg astronomical institute 2.5-m telescope will be installed.
Avila   +50 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Infection risk factor measurement based on spatial and temporal distribution of COVID-19 nucleic acid test sites: an example from Shenzhen

open access: yesFrontiers in Public Health
COVID-19 has profoundly impacted global daily life, emphasizing the need for effective virus suppression strategies. In response, China has established numerous nucleic acid testing sites to facilitate rapid testing and curb outbreaks.
Lei Wang   +3 more
doaj   +1 more source

Basic Protocol for On-Site Testing Consolidant Nanoparticles on Stone Cultural Heritage

open access: yesHeritage, 2019
Currently the application of consolidants based on nanoparticles is common practice among restorers. Consolidants should not modify the properties of original materials according to international recommendation, which requires previous studies to decide ...
Javier Becerra   +2 more
doaj   +1 more source

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