Results 181 to 190 of about 12,868,149 (415)

Residential child care in the spotlight: reflections on being involved in the BBC series 'social workers' [PDF]

open access: yes, 2004
Describes how a residential unit offering services for 8 children and young people became involved in the BBC Scotland series 'Social Workers', a fly-on-the-wall documentary about Edinburgh's Social Work Department. Discusses how the unit became involved,
McPheat, G.A.
core  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

'Nae too bad': job satisfaction and staff morale in Scottish residential child care [PDF]

open access: yes, 2005
In 2003, the National Children's Bureau and the Social Education Trust published a report - Better Than You Think -on staff morale, qualifications and retention in residential child care in England (Mainey, 2003a; Mainey, 2003b).
Avan, Ghizala   +3 more
core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Towards Synchronous Memorizability and Generalizability with Site-Modulated Diffusion Replay for Cross-Site Continual Segmentation [PDF]

open access: yesarXiv
The ability to learn sequentially from different data sites is crucial for a deep network in solving practical medical image diagnosis problems due to privacy restrictions and storage limitations. However, adapting on incoming site leads to catastrophic forgetting on past sites and decreases generalizablity on unseen sites. Existing Continual Learning (
arxiv  

An application of data mining to fruit and vegetable sample identification using Gas Chromatography-Mass Spectrometry [PDF]

open access: yes, 2012
One of the uses of Gas Chromatography-Mass Spectrometry (GC-MS) is in the detection of pesticide residues in fruit and vegetables. In a high throughput laboratory there is the potential for sample swaps or mislabelling, as once a sample has been pre ...
Fletcher, Dale   +2 more
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy