Results 271 to 280 of about 9,966,235 (337)

Landscape Structure and Breeding Site Conditions Shape the Urban Distribution of the Two Frog Species, <i>Dryophytes japonica</i> and <i>Rhacophorus schlegelii</i>. [PDF]

Ecol Evol
Osawa T, Sato N, Nagaoka H.
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Exploring the interplay between protein conformational changes and phosphorylation in a pancreatic cancer cell and stellate cell coculture system. [PDF]

Proc Natl Acad Sci U S A
Lu H, Liu Y, Chiang HY, Zhang H, Shi X, Li L.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Building Teaching Dispositions and Service-Learning Practice: A Multi-Site Study

, 2002
Susan Root, Jane Callahan, Jungsywan H. Sepanski   +2 more
openalex   +1 more source

Improving spliced alignment by modeling splice sites with deep learning. [PDF]

Algorithms Mol Biol
Yang S, Huang N, Li H.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

High-resolution HIV-1 m⁶A epitranscriptome reveals isoform-dependent methylation clusters and unique 2-LTR transcript modifications. [PDF]

NAR Genom Bioinform
Naquin D, Blanchet S, van Dijk E, Bertrand L, Grégoire S, Ramirez BC, Ouazahrou R, Jaszczyszyn Y, Moris A, Thermes C, Hernandez C, Namy O.   +11 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source