Results 281 to 290 of about 14,143,268 (384)

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Evaluating the Ecological Conditions of a Semi-Arid River Basin: A Multimetric Index Incorporating Fish and Macroinvertebrate assemblages. [PDF]

Environ Manage
Zare Shahraki M, Esmaeili Ofogh AR, Fathi P, Flotemersch J, Blocksom K, Bruder A.   +5 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Development of borated mesoporous zirconia nanocatalyst for the green synthesis of hydroquinone diacetate. [PDF]

Sci Rep
Ibrahim AA, Messiha YS, El-Hakam SA, Salama RS, Ahmed AI.   +4 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

On-surface synthesis of tailored organic platforms for single metal atoms. [PDF]

Nat Commun
Kinikar A, Xu X, Onishi T, Ortega-Guerrero A, Widmer R, Zema N, Hogan C, Camilli L, Persichetti L, Pignedoli CA, Fasel R, Narita A, Di Giovannantonio M.   +12 more
europepmc   +1 more source

Partial Order Optimum Likelihood (POOL): Maximum Likelihood Prediction of Protein Active Site Residues Using 3D Structure and Sequence Properties

, 2009
Wenxu Tong, Ying Wei, Leonel F. Murga, Mary Jo Ondrechen, Ronald J. Williams   +4 more
openalex   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Gap-Filling for Daily Latent Heat Flux Observations with the Full-factorial method at Global Flux Sites. [PDF]

Sci Data
Wang X, Tang F, Jiang Y, Lou Y.
europepmc   +1 more source