ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu+6 more
wiley +1 more source
THE POSSIBLE SITES OF RENIN FORMATION IN THE KIDNEYS OF THE EXPERIMENTAL HYPERTENSIVE RABBITS
FUJIO YOSHIMURA, Katsumi Shindo
openalex +2 more sources
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui+5 more
wiley +1 more source
mirTarCLASH: a comprehensive miRNA target database based on chimeric read-based experiments. [PDF]
Yang TH+5 more
europepmc +1 more source
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Candidate Sites for Millimeter and Submillimeter Ground-Based Telescopes: Atmospheric Rating for the Eurasian Submillimeter Telescopes Project. [PDF]
Shikhovtsev AY, Kovadlo PG, Baron P.
europepmc +1 more source
VI. An Account of various Roman Antiquities discovered on the site of the Church of St. Michael, Crooked Lane, and in Eastcheap, in forming the northern Approaches of the new London Bridge; communicated by Alfred John Kempe, Esq. F.S.A. in a Letter to Henry Ellis, Esq. F.R.S., Secretary [PDF]
Alfred John Kempe
openalex +1 more source
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu+4 more
wiley +1 more source
Sites ou pages web sur l’Espagne contemporaine
doaj +1 more source