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((معالجة المواقع الأخبارية العربية والدولية لقضية سد النهضة خلال الملء الأول والثاني (دراسة تحليلية ))) [PDF]

مجلة کلية الآداب. جامعة أسوان
استهدفت الدراسة التعرف على أطر معالجة المواقع الإخبارية لأزمة سد النهضة الأثيوبى ، وتعد هذه الدراسة من الدراسات الوصفية التى إستخدمت منهج المسح بشقه التحليلى وطبقت الدراسة على عينة عشوائية من المواقع الإخبارية الدولية والعربية ، وتمثلت فى ثلاثة مواقع وهى
شريهان مكي
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Nondestructive testing and assessment of consolidation effects of earthen sites

Journal of Rock Mechanics and Geotechnical Engineering, 2016
Earthen sites are widely distributed throughout China, and most of them belong to archaeological sites with significant values, which not only directly witness the origin, formation and development of Chinese civilization, but also possess important ...
Xudong Wang, Qinglin Guo, Shanlong Yang, Dexuan Zhang, Yanwu Wang   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Prevalence rate of white spot syndrome virus (WSSV) in farmed white leg shrimp (Litopenaeus vannamei) in Bushehr province

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2009
We surveyed presence of white spot syndrome virus (WSSV) in farmed white leg shrimp in Bushehr province with assumed a prevalence of 2% of virus in target population. Hence, 468 samples were collected in two separate phases from May to October 2006.
A. Ghajari; A. Seidi; K. Absalan fard; H. Yavari; M. Kosari
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Bleeding After Hospital Discharge Following Acute Coronary Syndrome: Incidence, Types, Timing, and Predictors

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The incidence and predictors of bleeding after acute coronary syndrome are unclear within the real‐world setting. Our objective was to determine the incidence, types, timing, and predictors of bleeding complications following hospital ...
Nafiu Ismail, Kelvin P. Jordan, Umesh T. Kadam, John J. Edwards, Tim Kinnaird, Mamas A. Mamas   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source