Results 241 to 250 of about 407,599 (315)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Physical activity and sitting time as correlates of cardiometabolic multimorbidity risk in U.S. adults: an explainable machine learning classification model using SHAP and LIME. [PDF]

BMC Public Health
Yang Y, Guo Z, Li D, Wu B, Xu C, Cai M, Wang Z.   +6 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Functional status, physical activity, pain, and multimorbidity among hospitalized adults aged 65 years and older: a cross-sectional study. [PDF]

Front Public Health
Majchrowicz B, Kowalczuk K, Rak R, Tomaszewska K.   +3 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Predictive Factors Associated With Dysphagia in Patients With Traumatic Brain Injury. [PDF]

Ann Rehabil Med
Yang SM, Lai TJ, Hsu YC, Lu YL, Chen HY, Tsai HT, Cheng SH, Hsiao MY, Lin MT.   +8 more
europepmc   +1 more source

ANALYSIS OF ARTHROPLASTIES IN ELDERLY PATIENTS WITH FEMORAL NECK FRACTURES AT A HOSPITAL IN SÃO PAULO. [PDF]

Acta Ortop Bras
Falcão MG, Suarez MA, Ferreira ACOP, Ranzoni LV, Iunes T, Terrível AM.   +5 more
europepmc   +1 more source

Performance measures across playing categories in competitive golfers with disabilities: a cross-sectional study. [PDF]

Front Sports Act Living
Jones KM, Wynter Bee W, Stenner B, Hawkes R, Wallace ES.   +4 more
europepmc   +1 more source

Medial Meniscus Physiologic Extrusion Across Sitting, Bipedal, and Unipedal Stance: The Roles of Generalized Hypermobility and Patellar Tendon Stiffness. [PDF]

Diagnostics (Basel)
Kilic KK, Kahvecioglu N, Yalcin M, Gurcan S, Kose O.   +4 more
europepmc   +1 more source