Results 61 to 70 of about 9,504,017 (340)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
U.S. Employment Situation Summary: June 2012 [PDF]
, 2012 Unemployment rate largely unchanged, youth, veterans, minorities and those with less education disproportionately ...
core
Integrative Psychological and Behavioral ScienceAbstract This article seeks to formulate a situated approach to mental disorder that overcomes some of the problems of contemporary diagnostic psychiatry. A framework is needed that aims to integrate neuroscientific knowledge about the brain and other aspects of the person with knowledge about the environment.
openaire +3 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Diversity-enhanced reconstruction as plug-in defenders against adversarial perturbations
Frontiers in Artificial IntelligenceDeep learning models are susceptible to adversarial examples. In large-scale deployed services, plug-in defenders efficiently defend against such attacks.
Zeshan Pang +7 more
doaj +1 more source
Solomon Islands national situation analysis [PDF]
, 2013 The CGIAR Research Program on Aquatic Agricultural Systems (CRP AAS) was approved by the CGIAR Fund Council in July, 2011. Solomon Islands, one of five countries targeted by the program, began its rollout with a five month planning phase between August ...
Govan, H. +3 more
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Situation Recognition with Graph Neural Networks
, 2017 We address the problem of recognizing situations in images. Given an image, the task is to predict the most salient verb (action), and fill its semantic roles such as who is performing the action, what is the source and target of the action, etc ...
Fidler, Sanja +5 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
On augment-less NPs in Xhosa and de NPs in French
Stellenbosch Papers in Linguistics Plus, 2019 Augment-less NPs in Xhosa and de NPs like de chevaux ‘of horses’ have strikingly similar properties. It seems that the properties of de NPs reflect the absence of the definite article les which combines with de to form the so-called partitive article des
Taraldsen, Knut Tarald
doaj +1 more source
A model and architecture for situation determination [PDF]
, 2006 Automatically determining the situation of an ad-hoc group of people and devices within a smart environment is a significant challenge in pervasive computing systems. Current approaches often rely on an environment expert to correlate the situations that
Nixon, Paddy +2 more
core +1 more source