Results 51 to 60 of about 70,483 (265)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Situational Privacy Concerns and Antecedent Factors
Journal of Computer Information Systems, 2016 ABSTRACTThis study examines the factors that contribute to context-based, or situational, privacy concerns drawing upon the theoretic lens of attribution theory. We posit that situational privacy concerns develop through individuals’ causal explanations of prior privacy incidents in addition to their trait-like, or dispositional, privacy concerns ...
Kayhan, Varol O., Davis, Christopher J.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Situational Factors in Safety Critical Software Development [PDF]
, 2016 The generic software development situational factors model has been developed in order that environments within which software is developed can be profiled and better understood. Situational context is a complex concern for software developers, with a broad set of situational factors holding the potential to affect any one software development project.
Risto Nevalainen +4 more
openaire +3 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Validation of Expanded Scale of Impulse Buying in Sports
Annals of Applied Sport Science, 2019 Background. Impulse buying is a complicated human buying behavior. It is influenced by factors such as income level, consumption pattern, lifestyle changes, sociocultural variables, and increased buying power.
Hosein Hasanpoor +2 more
doaj
Stylistyka, 2021 There is no unanimous point of view concerning the organic relationship between ‘style’ and ‘situation’, mainly because o f different definitions and interpretations of the concept o f ‘style’. As a quality of an integral text, style presents a text formulating modus, which characterizes new textual qualities that appear as optional to the basic ...
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source