Results 41 to 50 of about 53,510 (288)

Mental Imagery: Motivasi Belajar Siswa dalam Pembelajaran Pendidikan Jasmani

open access: yesPhysical Activity Journal, 2021
This research is motivated by the lack of student motivation in displaying the performance of Physical Education learning. The purpose of this study was to increase students' learning motivation in physical education learning through mental ...
Boby Agustan   +2 more
doaj   +1 more source

Potensi atas sumber daya perempuan terhadap program pelestarian Situs Manusia Purba Sangiran [PDF]

open access: yes, 2015
Kepemilikan lahan menjadi permasalahan penting dalam pengelolaan pelestarian Situs Sangiran di masa depan. Perempuan Situs Sangiran mempunyai peran domestik yang sangat melekat pada dirinya baik dalam kehidupan keluarga maupun masyarakat. Oleh sebab itu,
Adiati, Aththur Fithri
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Candi Cangkuang dan Masjid Agung Manonjaya Survei Kesejarahan Cagar Budaya di Jawa Barat

open access: yesBuletin Al-Turas, 2018
Among the most concrete. objective. authentic and unique historical evidences are the archeologist inheritance, whether temple, grave, epigraphy. artefac. and other things that support the truth and validity as a historical event. Cangkuang Temple is the
Nurhasan Nurhasan
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Effect of Aortic Arch Position on the Bronchial Length Ratio in Situs Determination

open access: yesCJC Pediatric and Congenital Heart Disease
Background: Bronchial length ratio (BLR) is widely used for situs determination. However, BLR may also be influenced by the position of the aortic arch. We aimed to evaluate the effect of aortic arch position on BLR.
Chae Young Kim, BHSc   +4 more
doaj   +1 more source

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