Results 81 to 90 of about 447,435 (164)

Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death

Virology Journal, 2010
While it has long been appreciated that there is considerable variability in host containment of HIV/SIV replication, the determinants of that variability are not fully understood.
Hsu Ariel, Chan Tiffany, Sundsvold TJ, Lim So-Yon, Rogers Thomas F, Letvin Norman L   +5 more
doaj   +1 more source

High‐Efficiency Graphene‐Silicon Slot‐Waveguide Microring Modulator at 1.5 and 2 µm Wavelength Bands

Laser &Photonics Reviews, Volume 20, Issue 19, 7 October 2026.
E/O modulators typically face a trade‐off between bandwidth and modulation efficiency. An integrated E/O modulator is presented that simultaneously achieves wideband, large bandwidth, and high modulation efficiency operation by embedding a partially overlapped double‐layer graphene on a compact silicon slot‐waveguide microring resonator.
Chao Luan, Deming Kong, Yong Liu, Yunhong Ding, Hao Hu   +4 more
wiley   +1 more source

Cholesterol 25‐Hydroxylase Deficiency Provides an Optimal and Durable Protective T Helper 1 Immunity via Interleukin‐12–Interleukin‐2 Axis in BCG‐Vaccinated Mice

MedComm, Volume 7, Issue 10, October 2026.
CH25H deficiency permits optimal dendritic cell activation following BCG exposure, characterized by increased IL‐12p70 production. In vivo, CH25H deficiency promotes enhanced BCG‐mediated protection and sustained IL‐2 producing T cell response. ABSTRACT Bacillus Calmette‐Guérin (BCG) remains the only licensed vaccine for tuberculosis (TB), yet its ...
Hagyu Kim, Eunsol Choi, Kee Woong Kwon, Hong‐Hee Choi, Kyungmin Kim, WeonSeok Jung, Sung Jae Shin   +6 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques

Virology Journal, 2012
Background An effective AIDS vaccine remains one of the highest priorities in HIV-research. Our recent study showed that vaccination of rhesus macaques with recombinant simian varicella virus (rSVV) vector – simian immunodeficiency virus (SIV) envelope ...
Pahar Bapi, Gray Wayne L, Phelps Kimberly, Didier Elizabeth S, deHaro Eileen, Marx Preston A, Traina-Dorge Vicki L   +6 more
doaj   +1 more source

Data from manuscript “Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection”

, 2018
Data file contains the animal information and quantitative image analysis results from our study of the early SIV-specific CD8 T cell responses during SIV infection.CD8+ T cells play an important role in controlling of HIV and SIV infections.
Skinner, Pamela J.
core   +1 more source

Protocol Deviations at an Academic Clinical Research Unit: Insights and Strategies for Prevention

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Protocol deviations threaten data integrity, regulatory compliance, and participant safety in clinical trials. Despite their prevalence, few longitudinal studies have characterized deviation patterns and described quality improvement strategies within clinical research units (CRUs).
Maran Subramain, Patrick Ten Eyck, Kristy Mahan, Jackline Wangui, Kimberly Sprenger, Donald G. McCloud Sr., John M. Buatti, Alejandro P. Comellas   +7 more
wiley   +1 more source

Changes in seasonal influenza vaccination uptake among older adults during and after the COVID-19 pandemic: Repeated random telephone surveys

Human Vaccines & Immunotherapeutics
People’s risk of contracting seasonal influenza increased after COVID-19 control measures were relaxed. This study investigated the changes in seasonal influenza vaccination (SIV) uptake and its determinants among older adults during and after the COVID ...
Xue Liang, Cichong Cai, Fuk-Yuen Yu, Danhua Ye, Yuan Fang, Phoenix K. H. Mo, Zixin Wang   +6 more
doaj   +1 more source

SIV-specific cell-mediated immune responses and PD-1 expression in PBMC T cells.

, 2018
A. Analyses for week 6 and week 60 after infection are shown. Group mean percentages of SIV-(Gag+Env)-specific CD4+ or CD8+ T cells of total CD4+ or CD8+ T cells ± SEM are indicated below each pie graph.
Ronald Veazey (3417311), Omkar Chaudhary (5703845), Felipe Lelis (5703848), Vivek Narayan (1543873), Anna Aldovini (241770), Brandon Linz (5703851), Meagan Watkins (5703854)   +6 more
core   +1 more source

Reaction‐Gated Transient Permeability in Ductile Shear Zones

Geophysical Research Letters, Volume 53, Issue 18, 28 September 2026.
Abstract Ductile shear zones act as transient pathways for crustal fluids, yet the conditions under which their connected porosity becomes sufficient to conduct are not well constrained. We present a porosity balance in which connected porosity evolves under three competing processes: creation by creep cavitation, creation by metamorphic reaction, and ...
Ioan V. Sanislav, Avish Kumar, Mabrouk Sami   +2 more
wiley   +1 more source