Results 111 to 120 of about 1,406,259 (307)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Математическое моделирование синхронной реактивной машины [PDF]

open access: yes, 2013
Approximation of experimentally captured dependencies Lk = f(θ,ik) are performed. Analytical expressions, taking into account the saturation induction, are found. The mathematical model of six-phase synchronous reluctance machine ШД-5Д1МУ3 are simulated.
Волянский, Роман Сергеевич   +2 more
core  

Topologically Massive Non-Abelian Gauge Theories: Constraints and Deformations [PDF]

open access: yes, 2001
We study the relationship between three non-Abelian topologically massive gauge theories, viz. the naive non-Abelian generalization of the Abelian model, Freedman-Townsend model and the dynamical 2-form theory, in the canonical framework.
A. Aurilia   +15 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Calculable CP-violating Phases in the Minimal Seesaw Model of Leptogenesis and Neutrino Mixing

open access: yes, 2003
We show that all nontrivial CP-violating phases can be determined in terms of three lepton flavor mixing angles and the ratio of $\Delta m^2_{\rm sun}$ to $\Delta m^2_{\rm atm}$ in the minimal seesaw model in which the Frampton-Glashow-Yanagida (FGY ...
Aalseth   +38 more
core   +2 more sources

Exact Solution of selfconsistent Vlasov equation [PDF]

open access: yes, 1997
An analytical solution of the selfconsistent Vlasov equation is presented. The time evolution is entirely determined by the initial distribution function. The largest Lyapunov exponent is calculated analytically.
Morawetz, K.
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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