Results 91 to 100 of about 4,304,091 (330)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Duke University Hospital: Organizational and Tactical Strategies to Enhance Patient Satisfaction [PDF]
, 2008 Highlights organizational and tactical strategies for realizing high patient satisfaction, including the use of communication boards in each room stating the plan of care, a "Balanced Scorecard" evaluation tool, and Six Sigma improvement ...
Sharon Silow-Carroll
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Six Sigma in Human Resource Management of Selected Organisation in Bangalore [PDF]
, 2014 The aim of the study is to examine the six sigma practices and its impact on strategic decision. Six sigma as a business process is now allowing organizations to improve their bottom line by designing and monitoring business activities in a way that ...
Rajesha, S.
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Jurnal Teknik Industri, 2007 The objective of this research was to minimize processing time in manufacturing using 5S (Seiri, Seiton, Seiso, Seiketsu, Shitsuke) method. As well as quality, processing time is one of the important points to consider. Improvement had been done in every
Adriansyah Adriansyah +2 more
doaj
, 1983 To survive in the competitive market, most organizations of today work with quality improvement of some kind in their business. Many organizations use concepts like Six Sigma and Lean, either applied as the structure for the entire improvement work, or ...
Ericsson, Evelina +2 more
core +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Primjena metodologije Six Sigma u logistici [PDF]
, 2012 U radu su opisane osnovne postavke Six Sigma metodologije s posebnim osvrtom na Six Sigma metriku. Također su navedene metode i alati koje Six Sigma metodologija koristi u cilju stalnog poboljšavanja kvalitete.
Topalušić, Marko
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