Results 31 to 40 of about 707,003 (287)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

PENDEKATAN SIX SIGMA UNTUK MENGURANGI PRODUK CACAT PADA PRODUKSI BOTOL DI CV XYZ

open access: yesSpektrum Industri: Jurnal Ilmiah Pengetahuan dan Penerapan Teknik Industri, 2019
CV. XYZ is a company engaged in consumer goods. In the production process, this company is still experiencing many problems. One of the problems faced is that there are still many defective products produced.
Nuri Kartini
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Implementing Six Sigma in Education [PDF]

open access: yesJournal of Islamic Studies, 2005
The purpose of this study was to try to implement six sigma in the educational sector. The results of the investigation, after reviewing the literature showed that education could benefit a great deal from six sigma theory; therefore, the researcher ...
Amal S. Al-Shaman
doaj  

Penerapan Metode Lean Six Sigma Dalam Upaya Rekrutmen Peserta PPU Badan Usaha: Study Kasus Proses Telemarketing Kantor Cabang Jakarta Selatan

open access: yesJurnal Jaminan Kesehatan Nasional, 2021
Pandemi covid-19 selama tahun 2020 membuat capaian peserta khusus segmen Pekerja Penerima Upah (PPU) mengalami penurunan, khususnya di kantor cabang Jakarta Selatan.Penelitian ini bertujuan untuk mengetahui dampak penerapan metode Lean Six Sigma dalam ...
Teguh Wijaya   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Design for six sigma: A review [PDF]

open access: yesManagement Science Letters, 2018
Six Sigma is recognized as an essential tool for continuous improvement of quality. A large num-ber of publications by various authors reflect the interest in this technique. Reviews of literature on Six Sigma have been done in the past by a few authors.
Kouroush Jenab   +2 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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