Results 51 to 60 of about 8,025,456 (269)

Determining the essential characetristics of Six Sigma Black Belts [PDF]

open access: yes, 2007
A Six Sigma Black Belt (SSBB) plays the role of a full-time team leader responsible for implementing process improvement projects using the Six Sigma methodology (Define-Measure-Analyse-Improve-Control) within the business to drive up customer ...
Antony, Jiju
core   +4 more sources

Modelo de referência para estruturar o Seis Sigma nas organizações Reference model to structure the Six Sigma in organizations

open access: yesGestão & Produção, 2008
Este artigo apresenta o modelo de referência para estruturar o Seis Sigma, o qual é resultante da incorporação de teorias que contribuem para aumentar o potencial estratégico do Seis Sigma no sentido de incrementar o desempenho organizacional.
Adriana Barbosa Santos   +1 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Adoção do Programa Seis Sigma em um Fornecedor Automotivo: Análise de Fatores Relevantes na Implementação

open access: yesTeoria e Prática em Administração, 2012
Since the development of the Six Sigma concept by Motorola in the 80’s many changes have made the market more competitive and demanding, especially in the automotive sector.
Miguel, Paulo Augusto Cauchick   +1 more
doaj  

Improvement of Motor Performance By Applying 6-Sigma (Dmadv) [PDF]

open access: yesEngineering and Technology Journal, 2015
Highly competitive markets justify the use of advanced technologies and methods to improve product’s quality and sales, which are the survival of any organization involved in business to be adaptive, proactive, and responsive to changes and has the ...
May George Kassir, Shatha Mouayad Mahdi
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Lean six sigma implementation in a yarn textile industry

open access: yesGEPROS: Gestão da Produção, Operações e Sistemas, 2017
Due to fierce competition from companies in achieving larger market share, there is an increasing interest regarding cost reduction, efficiency in business and processes, increase in quality and continuous improvement.
Rayra Rodrigues Nogueira   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Program Assessment Using Six Sigma Green Belt Certification Requirements [PDF]

open access: yes2015 ASEE Annual Conference and Exposition Proceedings, 2015
Title: Program Assessment Using Six Sigma Green Belt Requirements Abstract: Manufacturing oriented programs shape industrial practices through educated graduates. In turn manufacturing educators look to practice for opportunities to refine and improve curriculum.
Christopher P. Pung, Hugh Jack
openaire   +2 more sources

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