Results 71 to 80 of about 17,889,374 (275)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

«Horrendum scelus, piaculare flagitium in partibus Calabrie». Il caso di Federico, vescovo di Bisignano (XIV secolo)

open access: yesPeloro
Nella Calabria di primo Trecento, caratterizzata da forte instabilità sociale e teatro di drammatici scontri, in particolare tra potere laico e religioso, un episodio spicca per gra­vità e crudeltà, l’uccisione di Federico, vescovo di Bisignano nel ...
Claudia Ercoli
doaj   +1 more source

El amor cristiano en la Tragicomedia de Fernando de Rojas y en la Segunda Celestina de Feliciano de Silva

open access: yesCelestinesca, 2019
El presente trabajo se propone explorar la percepción del amor en el contexto cristiano, con el intento de reconocer la implementación y los cambios de costumbres que se evidencian en dos producciones literarias que tienen como protagonista a Celestina:
Petre Ene
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Class Size Controversy [PDF]

open access: yes, 2001
[Excerpt] When we ask whether class size matters for achievement, it is essential to ask also, how class size matters. This is important for three reasons.
Brewer, Dominic J.   +3 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Comparison of Color Doppler Ultrasound Characteristics between Parotid Mucoepidermoid Carcinoma and Basal Cell Adenoma

open access: yesJournal of Medical Ultrasound
Knowledge of the color Doppler ultrasound (US) characteristics of parotid malignant mucoepidermoid carcinoma and benign basal cell adenoma remains limited.
Shubao Chen, Size Wu
doaj   +1 more source

La Celestina en la Transición. Censura, polémica e interpretación de la recreación telefílmica de Juan Guerrero Zamora

open access: yesCelestinesca, 2019
El artículo se propone examinar, en primer lugar, los problemas que atravesó el guion de la recreación cinematográfica basada en La Celestina de Juan Guerrero Zamora durante el franquismo.
José Eduardo Villalobos Graillet
doaj   +1 more source

Kubo formula for finite size systems

open access: yes, 2010
We demonstrate that the proper calculation of the linear response for finite-size systems can only be performed if the coupling to the leads/baths is explicitly taken into consideration.
Berciu, Mona, Wu, Jinshan
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy