Results 61 to 70 of about 25,853 (250)

Aging Salamandrina perspicillata (Savi, 1821) by skeletochronology

open access: yesActa Herpetologica, 2007
We assessed age and first reproduction age in Salamandrina perspicillata females by means of skeletochronological analysis. As we examined sections from the third toe of the hind limbs, the tecnique herewith introduced is non-letal and compatible with ...
Stefano Bovero   +2 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

ONTOGENETIC DEVELOPMENT OF SAGITTA OTOLITHS IN EUGERRES BRASILIANUS (CUVIER, 1830) (ACTINOPTERYGII: GERREIDAE) WITH EMPHASIS ON SIZE AT FIRST SEXUAL MATURITY IN A COASTAL LAGOON IN SOUTHEASTERN BRAZIL

open access: yesArquivos de Ciências do Mar
Avaliações do desenvolvimento de otólitos relacionado a história de vida de peixes buscam prover informações importantes para compreensão da variabilidade intraespecífica dessas estruturas. Neste contexto, o presente trabalho buscou identificar padrões ontogenéticos e sexuais na morfologia dos otólitos de Eugerres brasilianus capturados na lagoa de ...
Daniella Hunder de Andrade   +4 more
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Distribution and first insight into the reproductive biology of two species of the genus Rhamdia (Siluriformes, Heptapteridae) in a Biosphere Reserve [PDF]

open access: yesNeotropical Biology and Conservation
Distribution data and reproductive biology of freshwater catfishes of the genus Rhamdia remain insufficiently explored, limiting our knowledge of these ecologically, nutritionally, and economically important species.
César C. Julián-Caballero   +4 more
doaj   +3 more sources

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