Results 71 to 80 of about 25,853 (250)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Reproductive biology of the rock goby, Gobius paganellus (Actinopterygii: Perciformes: Gobiidae), on the southern Tunisian coast (Gulf of Gabes)

open access: yesCiencias Marinas, 2012
The rock goby Gobius paganellus is one of the most common gobiid fish on the southern Tunisian coast and this study provides the first detailed information on its reproductive biology in the Gulf of Gabes.
F Hajji   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Aspects of the reproductive biology of the freshwater/brackish amphipod Quadrivisio lutzi (Crustacea, Amphipoda) from an unstable coastal lagoon of southeastern Brazil

open access: yesNauplius
The amphipod Quadrivisio lutzi (Shoemaker, 1933) (Maeridae) inhabits the coastal lagoons of southeastern Brazil, which are highly unstable environments.
Taiane Barreiro Medeiros   +1 more
doaj   +1 more source

The growth and reproductive biology of the coral gall crab, Hapalocarcinus marsupialis Stimpson, 1859 (Crustacea: Cryptochiridae) from Gulf of Aqaba, Red Sea, Egypt

open access: yesJournal of Basic and Applied Zoology, 2018
Background Gall crabs were described 150 years ago, but little is known about their biology, ecology, and taxonomy. Studying the breeding season can facilitate the understanding of the adaptive strategies and reproductive potential of gall crab and its ...
Khaled A. El-Damhougy   +3 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Age-size relationship at reproduction of South African female loggerhead turtles Caretta caretta

open access: yesEndangered Species Research, 2014
Average age and size at first reproduction are important demographic parameters used in the management and conservation of populations. For sea turtles, absolute values for these parameters are still ambiguous, as most species are slow-growing, late ...
J Tucek, R Nel, M Girondot, G Hughes
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Reproduction of the Brazilian snapper, Lutjanus alexandrei Moura & Lindeman, 2007 (Perciformes: Lutjanidae), off the northern coast of Pernambuco, Brazil

open access: yesNeotropical Ichthyology, 2012
Reproductive aspects of the Brazilian snapper Lutjanus alexandrei, were characterized, including a description of the development of oocytes and spermatogenic cells, size at first sexual maturity, and fecundity. A total of 540 fish were analyzed with 250
Cezar A. F. Fernandes   +3 more
doaj  

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