Results 131 to 140 of about 633,140 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Size Effect of Shear Bands in Dense Sands—A Discrete Element Analysis

Applied Sciences
The localization of deformation in shear bands is a fundamental phenomenon in granular materials like soil. In this study, we focus on the characteristics of shear bands, particularly the size effect, by implementing biaxial discrete element method (DEM)
Zongyuan Mao, Luqian Zhang, Ning Zhang, Lihong Chen   +3 more
doaj   +1 more source

Teacher experience and the class size effect - experimental evidence [PDF]

We analyze teacher experience as a moderating factor for the effect of class size reduction on student achievement in the early grades using data from the Tennessee STAR experiment with random assignment of teachers and students to classes of different ...
Mueller, Steffen
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Is optimization an opportunity ? an assessment of the impact of class size and school size on the performance of Ukrainian secondary schools [PDF]

Using a rich data set of almost the entire population of Ukrainian secondary schools, the authors estimate the effect of school size and class size on the performance of secondary schools on Ukraine's External Independent Test.
Alonso, Juan Diego, Coupe, Tom, Olefir, Anna   +2 more
core   +2 more sources

Advances in coinage metal nanoclusters: From synthesis strategies to electrocatalytic performance

Polyoxometalates
Due to the powerful quantum confined space effects and multiple modes of small atomic sizes, metal nanoclusters (NCs) like thiolate-protected noble metals, such as silver (Ag) and gold (Au), which have a core sizes less than 3 nm, have developed a class ...
Piracha Sanwal, Ali Raza, Yu-Xin Miao, Brock Lumbers, Gao Li   +4 more
doaj   +1 more source

Micrometre-scale plasticity size effects in metals and ceramics: theory and experiment.

, 2009
PhDThis thesis comprises studies of size effects in the plasticity of metals and ceramics at length scales of the order of micrometres and includes both experimental work and theoretical development. Experimental results are presented for foil flexure
Zhu, Tingting
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Birth Order Matters: The Effect of Family Size and Birth Order on Educational Attainment [PDF]

We use unique retrospective family background data from the 2003 wave of the British Household Panel Survey to explore the degree to which family size and birth order affect a child’s subsequent educational attainment. Theory suggests a trade off between
Hiau Joo Kee, Alison Booth
core