Results 141 to 150 of about 633,140 (259)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
New Evidence on Class Size Effects : A Pupil Fixed Effects Approach [PDF]
The impact of class size on student achievement remains a thorny question for educational decision makers. Meta-analyses of empirical studies emphasise the absence of class-size effects but detractors have argued against such pessimistic conclusions ...
Nadir Altinok, Geeta Kingdon
core +2 more sources
On the misinterpretation of effect size [PDF]
Educational Studies in Mathematics, 2019 openaire +3 more sources
CLASS SIZE EFFECTS ON STUDENT ACHIEVEMENT: HETEROGENEITY ACROSS ABILITIES AND FIELDS [PDF]
In this paper we analyze class size effects on college students exploiting data from a project offering special remedial courses in Mathematics and Language skills to freshmen enrolled at an Italian medium sized public University. To estimate the effects
Michela Ponzo +2 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Neural correlates of the orthographic neighborhood size effect in Chinese
, 2010 Word recognition research with alphabetical scripts has revealed a facilitatory neighborhood size effect, whereby naming of words with more orthographic neighbors is faster than that of words with fewer neighbors.
Bi, Hong-Yan +3 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Revisiting the size effect in the Bovespa
RAE: Revista de Administração de Empresas, 2017 The size effect has been analyzed in numerous stock markets using different approaches. However, there are few studies focused on its practical applicability. In this context, the aim of this study is two-fold.
Maria del Mar Miralles-Quiros +2 more
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source