Results 101 to 110 of about 16,450,513 (295)
The effects of striped clothing on perceptions of body size
Findings in recent studies indicate that, contrary to popular fashion advice, horizontal lines do not give the impression of larger body size (Thompson, 2008; Thompson & Mikellidou, 2009, 2011).
Swami, V., Harris, A.S.
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Makaleleri değerlendirirken istatistiksel önemlilik yani p değeri dikkate alınan bir ölçüttür. Buna karşılık en az istatistiksel önemlilik kadar önemli olan klinik önemlilik yazarlarca veya okurlarca her zaman dikkate alınmayan bir durumdur. Bu makalede klinik önemi gösteren önemli bir ölçüt etki büyüklüğü kavramı, hesaplanması ve yorumlanması ile ...
+6 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Size effect on the fundamental properties of Sn2P2S6 ferroelectric is studied. The decrease of Raman peak frequency, accompanied by the band broadening and asymmetry, is observed in the spectra of microcrystalline Sn2P2S6 powder. Theoretical calculations,
A.V.Drobnich +4 more
doaj +1 more source
The power of effect size stabilization
Determining an appropriate sample size in psychological experiments is a common challenge, requiring a balance between maximizing the chance of detecting a true effect (minimizing false negatives) and minimizing the risk of observing an effect where none exists (minimizing false positives).
openaire +2 more sources
The Size-Dependent Elastic Properties of Nanofilms with Surface Effects
Size-dependent elastic constants are investigated theoretically with reference to a nanoscale single-crystal thin film. A three-dimensional _3D_ model is presented with the relaxation on the surface of the nanofilm taken into consideration.
Zhao, YP (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100080, Peoples R China. +2 more
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

