Results 141 to 150 of about 372,530 (379)

Development and validation of a simple and sensitive size-exclusion chromatography method for quantitative determination of heparin in pharmaceuticals

Acta Pharmaceutica, 2015
Heparin is widely used as an anticoagulant for the treatment and prevention of various thrombotic diseases. However, due to its high anionic charge, heterogeneity in size distribution and high polarity, its analysis is very challenging.
Matanović Maja Radivojša, Grabnarm Iztok, Grabnar Pegi Ahlin, Roškar Robert   +3 more
doaj   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

The influence of long-term inputs of catch crops and cereal straw on yield, protein composition and technological quality of a spring and a winter wheat [PDF]

, 2011
Under conditions of restricted nitrogen (N) input such as in organic farming systems, crop N uptake must rely on N mineralised from applied animal manure, crop residues and native soil organic matter.
Carcea, M., Narducci, V., Samson, M.-F., Thomsen, I.K.   +3 more
core  

Size-exclusion chromatography small-angle X-ray scattering of water soluble proteins on a laboratory instrument

Journal of Applied Crystallography, 2018
Size-exclusion chromatography coupled with a laboratory-based small-angle X-ray scattering setup is presented and its performance evaluated for studies of various proteins covering a broad range of molecular weights.
Saskia Bucciarelli, S. Midtgaard, Martin Nors Pedersen, Søren T Skou, L. Arleth, B. Vestergaard   +5 more
semanticscholar   +1 more source

Ultrahigh‐Yield, Multifunctional, and High‐Performance Organic Memory for Seamless In‐Sensor Computing Operation

Advanced Functional Materials, EarlyView.
Molecular engineering of a nonconjugated radical polymer enables a significant enhancement of the glass transition temperature. The amorphous nature and tunability of the polymer, arising from its nonconjugated backbone, facilitates the fabrication of organic memristive devices with an exceptionally high yield (>95%), as well as substantial ...
Daeun Kim, Jaehyoung Ko, Namju Kim, Quynh H. Nguyen, Hoyeon Lee, Joohwan Eo, Seongeon Jin, Ji Eon Kwon, Seung‐Yeol Jeon, Youngdo Jeong, Dongseok Kwon, Sung Gap Im, Sanghan Lee, Byung Chul Jang, Yongho Joo   +14 more
wiley   +1 more source

Multimode chromatography‐based techniques for high purity isolation of extracellular vesicles from human blood plasma

Journal of Extracellular Biology
Extracellular vesicles (EVs) play a pivotal role in various biological pathways, such as immune responses and the progression of diseases, including cancer.
Alan J. Zimmerman, Getulio Pereira deOliveira Jr., Xianyi Su, Jacqueline Wood, Zhengxin Fu, Brandy Pinckney, John Tigges, Ionita Ghiran, Alexander R. Ivanov   +8 more
doaj   +1 more source

Chemoselective Sequential Polymerization: An Approach Toward Mixed Plastic Waste Recycling

Advanced Functional Materials, EarlyView.
Inspired by biological protein metabolism, this study demonstrates the closed‐loop recycling of mixed synthetic polymers via ring‐closing depolymerization followed by a chemoselective sequential polymerizations process. The approach recovers pure polymers from mixed feedstocks, even in multilayer formats, highlighting a promising strategy to overcome a
Gadi Slor, Youwei Ma, Hyunwoo Park, Tae‐Lim Choi, Damien Guironnet, Francesco Stellacci   +5 more
wiley   +1 more source

Beyond size exclusion: online liquid chromatography for BioSAXS [PDF]

, 2017
Martha Brennich, Stephanie Hutin, Katharina Weinhäupl, Paul Schanda, Petra Pernot   +4 more
openalex   +1 more source

Scalable purification of extracellular vesicles with high yield and purity using multimodal flowthrough chromatography

Journal of Extracellular Biology
Extracellular vesicles (EVs) are cell derived membranous nanoparticles. EVs are important mediators of cell–cell communication via the transfer of bioactive content and as such they are being investigated for disease diagnostics as biomarkers and for ...
Scott E. Bonner, Simonides I. van deWakker, William Phillips, Eduard Willms, Joost P. G. Sluijter, Andrew F. Hill, Matthew J. A. Wood, Pieter Vader   +7 more
doaj   +1 more source